Outlined below are the clinical questions formulated according to the information provided in the protocol, which was revised and accepted by the Protocol Advisory Subcommittee (PASC) of the MSAC.
Research questions:
What are the safety, effectiveness, and cost-effectiveness of NAAT versus NAAT plus AFB microscopy in diagnosing TB in patients who have signs and symptoms of TB?
What are the safety, effectiveness, and cost-effectiveness of NAAT versus current testing in diagnosing NTM in patients suspected of having an NTM infection?