For some of the trials, radiology images will be generated, in particular PET/CT images. PET-CT (Positron Emission Tomography – Computed Tomography) images are acquired in a device that combines detectors for the two modalities. The two images are then fused during co-registration. The FDG-PET part of the composite image allows the detection of anatomical regions with high metabolic activity, most prominently primary tumours and metastases, while the CT part of the composite image allows precise localisation of the anatomical structures and the tumours and metastases. PET/CT images are stored in the DICOM format. In some cases the contours of the primary tumour and other anatomical regions and landmarks of interest will have been delineated by a doctor (stored as a DICOM Structured Report).
