Prevention of radiation-induced hepatic damge on swiss albino mice by aloe vera leaf extract

Fig.3: Glutathione level in blood and liver after 6 Gy of γ-irradiation with

(Experimental) or without (Control) AVE

Liver-LPx:

A dose dependent elevation in LPx level in terms of thiobarbituric acid reactive substances (TBARS) or malondialdehyde (MDA) was measured in the control animals. This increase was more at higher dose than the lower doses of gamma radiation. AVE pretreatment inhibited such increase in LPx level as it was found to be significantly lower than the corresponding controls.

Serum-LPx:

No significant alterations in LPx level of serum were observed in normal and AVE treated animals. In the control animals, a dose dependent increase in TBARS was noted following irradiation, and such values were found to be significantly higher than the normal. However, in AVE pretreated irradiated animals (Group-IV), such level was found to be significantly below the respective controls (Fig. 4).

C

C

Fig.4: Variation in LPO level after 6 Gy of γ-irradiation with (Experimental) or

without (Control) AVE