#The most dangerous complication of ace inhibitor therapy

TESTS WITH THREE ANSWERS

#Specify the drug used for the relief of hypertensive crisis:

+ clonidine
+ nifedipine
+ captopril
-reserpine
-propranolol
-valsartan

#Specify the main principles of drug treatment of hypertension:

+ use of extended preparations
+ optimal combination of drugs
-fast blood pressure reduction
+ start with minimal doses
- course admission
-beginning with the target dose

#Ideal hypotensive agent must meet the following requirements:

+ decrease in blood pressure is proportional to the dose
+ cause long-term effects
+ synergist be with other antihypertensives
-increasing oxygen supply to the myocardium
-fast lower blood pressure
-call postural hypotension

#Specify the most effective combinations of antihypertensive drugs:

-beta-blockers + verapamil
+ diuretics + beta-blocker
+ diuretics + ACE-inhibitors
+amlodipine + beta-blockers
-alpha-blocker + calcium antagonist
-beta-blockers + imidazoline agonists

#Principles of treatment of hypertension in the elderly:

+ is not used drugs that cause orthostatic hypotension
-drug treatment only during crises
+ drugs of choice - dihydropyridine calcium antagonists
-preparat choice - beta-blockers
+ target blood pressure - 140/80 mm Hg
-preparat choice - ACE inhibitors

#By the pharmacodynamic effects of NSAIDs include:

+ antipyretic
-hypotenziv
+ analgesic
-gipoholesterolemic
+ anti-inflammatory
-proagregant

#What are the antihypertensive drugs are contraindicated for pregnant women?

-gidralazin
+ valsartan
-metoprolol
+ reserpine
+lisinopril
-methyldopa

#What are contraindications to nitrates:

+ glaucoma
-arterial hypertension
+ intracranial hypertension
+ low systolic blood pressure (less than 90 mm Hg)
-heart failure
-bronchial asthma

# What are the indications Cholagogue:

-ulcer bleeding
+ chronic pancreatitis
-nonspecific ulcerative colitis
+ hypoacid gastritis
-chronic hyperacid gastritis
+ constipation

# Name the pharmacodynamic effects of ursodeoxycholic acid:

+ direct hepatoprotective effect
-appear antidiarrhoeal action
-appear cytoprotective effect
+ dissolves stones holesterolovye
+ has choleretic action
-increase cholestasis

# Name the methods of monitoring the safety of statin therapy:

+ control of creatine phosphokinase levels
-control urate level
+ constant observation ophthalmologist
- observation neurologist
- observation nutritionist
+ liver function tests

# Name the pharmacodynamic effects of simvastatin:

+ inhibits cholesterol biosynthesis
+ reduces the synthesis of VLDL
-it reduces the content of HDL
+ lowers triglycerides
-do not metabolized
-is ion exchanger

# What are assigned diuretics in chronic heart failure:

+ loop diuretics
+ direct aldosterone antagonists
-osmotic diuretics
+ thiazide diuretics
-ingibitory carbonic anhydrase
-nepryamye aldosterone antagonists

# Specify the drugs that increase life expectancy in patients with chronic heart failure:

+ ACE-inhibitors
-heart glycosides
+ beta-blockers
+ aldosterone antagonists
-diuretics
-antiagregants

# Specify the main pharmacodynamic effects of heparin:

-blocking synthesis of prothrombin
+ inactivated factors IX, X, XI, XII
+ acts in vitro and in vivo
+ blocks the conversion of prothrombin to thrombin
-inactivation factors II, VII, IX, X
-actions only in vivo

# What are the main characteristics of dipyridamole:

+ non-nitrate coronary vasodilator
-ingibits prostaglandin synthesis
+ acts on the small coronary vessels
+ inhibits platelet aggregation
-ingibits cyclooxygenase
-level of fibrinogen

# Name antibacterials prescribed for acute exacerbations of COPD associated with lower respiratory tract infections:

+ respiratory fluoroquinolone
+ macrolides
+ protected aminopenicillins
-linkozamids
-oksazolidinons
-aminoglikozids

# Specify the antibiotics I-st ​​line treatment of purulent bronchitis:

+ aminopenicillins +inhibitors of beta-lactamase
+ fluoroquinolones
+ II- III generation cephalosporins
-aminoglikozids
-nitrofurans
-rifampitsin

# What are antibiotics used for the treatment of nosocomial pneumonia:

+ aminoglycosides
+ carbapenems (imipenem / silastin)
+ cephalosporins III-IV generation
-aminopenitsillins
-makrolids
-sefalosporins I generation

# Name preparations which can be used for treatment of complicated urinary tract infections:

+ cephalosporins 3rd generation
+ imipenem (tsilastin)
+ fluoroquinolones
-nalidiks acid
-amoksitsillin
-ko-trimoxazole

# Mark characteristic aminoglycoside side effects:

-anemiya, thrombocytopenia
-porazheniya liver
+ hearing loss
+ vestibular disorders
+ nephrotoxicity
-uhudshenie view

#Specify the side effects characteristic of vancomycin:

-psevdomembranoz colitis
+ ototoxicity
+ nephrotoxicity
+ syndrome "red man"
-hepatotoxisity
-anemia

#To antiasthmatic anti-inflammatory drugs include:

-beta-2 agonists
+ cell membrane stabilizers
-expectorants
+ leukotriene inhibitors
-metilksantins
+ steroids

#Side effects of theophylline:

-gipoglikemiya
+ metabolic acidosis
-metabolic alkolozis
+ irritability, hallucinations
+ tachycardia
-bradikardiya

#Pereparats III generation antihistamines:

-cetirizin
+ levocetirizine
-loratadin
+ fexofenadine
+desloratadine
-tavegil

# Theophylline is contraindicated in:

-gipotireoz
+pregnancy
-chronic bronchitis
+ hypotension, collapse, shock
-ischemic stroke
+ lactation

# Phosphodiesterase inhibitors are contraindicated in:

+ epilepsy
-glaucoma
-ostraya pneumonia
+ acute myocardial infarction
-arterial hypertension
+ thyrotoxicosis

# Mucolytics generation 1have the following properties:

-improves mucociliary clearance
+ reduce the elasticity of the secret
-increasethe synthesis of surfactant
-stimulyation acetylcholine
+ breaks the disulfide bonds
+ reduce the viscosity of secretions

#Select the components of treatment asthma attack:

+methylprednisolone / 1-5 mg / kg
+eufillin 2,4% -10 ml / jet
-intal every 20 minutes
-atrovent
-eufillin 24% - 1 ml
+ salbutamol every 20 min

# To antileukotriene drugs include:

-feksofenadin
+ zafirlukast
-roflumilast
+ montelukast
+ zileuton
-ketotifen

# What are the 3 indications of lidocaine

-weakness sinus
+ ventricular tachycardia, ekstrasitoliya
+ prevention of ventricular arrhythmia in acute myocardial infarction
-2 and 3 degree AV blockade
+ decrease in heart rate in atrial fibrillation
-full AV block

#Specify the main side effects of Amiodarone

+ microcalcifications in the cornea, photophobia
-ventricular arrythmia
+ photosensitivity
+ arrhythmogenic effect, bradycardia
- gynecomastia
-bronhospazm

#What are the indications prokainamide

+ ventricular and supraventricular paroxysmal tachycardia
-full AV block
+ flutter and atrial fibrillation
+ WPW syndrome
-ventricular arrhythmia during digitalis intoxication
-violation intraventricular conduction

# Specify 3 pharmacodynamic effect of propranolol

-increase the sinus node automaticity
+ decrease in cardiac output
+ membrane-stabilizing effect
-decrease HR
+ decrease in sinus automatism
-improved conduction in the AV node

# Name the drugs that are used in atrial arrhythmia politopnye:

-flekainid
+ metoprolol
+ verapamil
-difenin
+ amiodaron
-lidokain

# What are the 3 main indications for benzodeazepinov:

+ alcohol withdrawal
-dementsiya
+ anxiety and insomnia
-epistatus
+ manic psychosis
-pregnancy

#List 3 main indications for antidepressants:

+ depression
-epilepsy
+ cardiopsychoneurosis
+ alarm
-maniakal-depressive psychosis
-violation sleep

# Name the three drugs that are antidepressant:

+ imipramine
-droperidol
+ amitriptyline
-adrenalin
+ klamipramin
-benzonale

# What are the 3 absolute contraindications to the use of hormonal contraceptives:

-arterialnaya hypotension
+pregnancy
-diabetes
+ allergic reactions
-infertility
+ individual intolerance

Call # 3 antihypertensive drugs used during pregnancy

-enalopril
-valsartan
+ verapamil
+ metoprolol
+ methyldopa
-reserpine

# What are the principles of treatment of hypertension in patients with diabetes:

+ BP below 130/85 mm Hg
- choice drug - a diuretic + beta-blocker
+ choice drug - ACE inhibitors
-use thiazide diuretics
+ choice drug - the AT-1, AT-II blockers
- choice drug- beta-blockers

# Name the drugs used in pulmonary edema:

-klofelin
+ nitroprusside
+ furosemide
-mannit
-verapamil
+ strophanthin

# What are the side effects of captopril:

-leykotsitoz
-trombotsitoz
+ taste disturbance
+ dry cough
+ angioedema
-bradikardiya

# Development of hypertension most commonly provokes taking medicines:

+ NSAIDs
-H2 Histamine receptor blockers
-antibakterial drugs
+ oral contraceptives
+ steroids
-heartglycosides

# Reasons for resistance to diuretics in chronic renal failure:

-blokada prostaglandins
+ reduction in existing nephrons
+ relationships with urine protein
-blokada prostacyclin
+ decrease in glomerular filtration rate
-podavlenie intrarenal kallekrein-kinin system

# Name the drugs used to eradicate H.pilory:

+ proton pump inhibitors
+ clarithromycin amoksicillin
-eubiotics
-spazmolitic
+ bismuth drug
-antatsids

# What are the cardiac glycosides can be used in patients with kidney disease?

+ atsetildigitoksin
-korglikon
+ digoxin
+ digitoksin
-strofantin
-izolanid

# A combination of any rational diuretics for CHF FC II:

+ torasemide+ veroshpiron
+ furosemide +indapamide
-manitol + furosemide
-diakarb + hydrochlorothiazide
+ furosemide + spironolactone
-diakarb + mannitol

# Beta-blockers can be used for the following diseases, leading to heart failure:

+ hypertension
+ hypertrophic cardiomyopathy
-dangerous hypertension
-diabetes
+ myocardial infarction
-vasospastic angina

# What are the rules of appointment of heparin:

-first dose of 50 thousand.Unit
+ the first dose of 15 thousandUnit
+activated partial thromboplastin time increased 1.5 times
-activated partial thromboplastin time increases 5 times
+ blood clotting time increases 2 times
-blood clotting time Increases 5 times

# Nephrotoxicity are all listed antibiotics, except for:

+ tetracycline
+ medikamitsin
-gentamitsin
-amikatsin
+ ceftriaxone
-kanamitsin

# Children under 14 years are contraindicated:

-ampitsillin
+ tetracycline
-eritromycin
+ciprofloxacin
+ levofloxacin
-cefazolin

# Patients with neuritis of the auditory nerve are contraindicated:

-ampitsillin
+ streptomycin
-erytromitsin
+ gentamicin
+ kanamycin
-sefazolin

# Name of fluoroquinolone antibiotics

- oxacillin
+ pefloksatsin
- erythromycin
+ ofloxacin
+ levofloksftsin
-sefoperazon

# When using rifampicin painted in red:

-lymph
+ urine
+ tears
- bili
-saliva
+ sputum

# Name of the cephalosporin group of antibiotics:

-metitsillin
-oksatsillin
+ cefazolin
+cefepime
-tsiprofloksatsin
+ cefuroxime

# Name of the antibiotics group karbopinems:

-oksasillin
+ imipinem
- erythromycin
+ meropinem
-karbenisillin
+ ertapenem

# Name the drugs are not used for children up to 16 years:

+ciprofloxacin
-tsefazolin
-ampitsillin
+ levofloxacin
+ moxifloxacin
-klaritromitsin

# Name antibiotics from the group of sulfonamides:

-metitsillin
+ ftalazol
- erythromycin
+ sulfasalazine
+ sulfalen
-cefoperazon

# Specify the 3bronchodilator group:

-inhalyasion steroids
+ methylxanthines
+ beta 2 agonists
-membranostabilizators
+ anticholinergics
-antileykotriens

# Specify 2 mucolytics generation:

-mukaltin
+ ambroksol
+ bromhexinum
-bronholitin
+ lasolvan
-terpingidrat

# What are the side effects of flunisolide:

-arterial hypertension
+ dysphonia
+ oral candidiasis
-bronhoreya
+ cough
-diabetes

# Indications mast cell stabilizers:

-holinergic asthma
+ drugs of choice in children
-preparat choice in pregnant women
+ apply only prophylactically
+ hay fever
-for relief of asthma attack

# From what indicators depends danger of overdosing?

+ therapeutic index
+ breadth of therapeutic action
-complete absorption
-time to maximum concentration
+ dosing regimen
-half-life-period

# Specify the macrolide drugs:

+ erythromycin
+ azithromycin
-amoksitsillin
-etrapenem
+ clarithromycin
-sparfloksatsin

# With the sudden cancellation of the drug raises the following adverse reactions:

+ drug dependence
+ withdrawal
-teratogenic effect
-embrioxicity
+Ricochet effect
-idiosyncrasy

# Side effects of type D include:

+ carcinogenic effect
+ embritoxycity
+ teratogenic
-idiosyncrasy
-increased sensitivity
-syndrome cancel

# What are antibiotics that can be used during pregnancy

-ftorhinolon
-aminoglikozids
+ cephalosporins
+ macrolides
+ penicillins
-tetratsiklin

# Specify the indications for barbiturates:

+ anxious
+ epilepsy
-alkogol withdrawal
-pain syndrome
+insomnia
-rvota pregnant

# Specify the side effects of iron supplements, observed in the use of inside:

+ staining stool black
-blood in feces
+ staining of urine black
-colored urine reddish color
+ dyspepsia
-disbakterioz

# Name of cephalosporin drugs 3 generations

+ seftiakson
-siprofloksatsin
+ ceftazidime
-sefuroksim
+ cefixime
-sefepim

# Specify the side effects associated with the use of oral contraceptives:

-hair loss
+ hypertension
-disbakterioz
+ nausea
-dry skin
+ tendency to thrombosis

# Name the drugs used to treat gout:

+ colchicine for pain relief
+ probenicid
-delagil
+ alopurinol
-nicotinic acid
-gipotiazid

#Call 3 states in which thiazides are the drugs of choice for hypertension:

+ elderly patients
+ obese
+ marked sodium retention
- patients with hyperuricemia
- patients with diabetes
- patients with hyperlipidemia

# What are the 4 conditions for which beta-blockers are the drugs of choice for hypertension:

+pregnancy
+ hyperkinetic type of circulation
+ angina
- patients with diabetes
- patients with hyperlipidemia
-bronhoobstruktiv syndrome

# Call 3 condition in which ACE inhibitors are the drugs of choice for hypertension:

+ diabetes
+ circulatory failure
+ renovascular hypertension
-pregnancy
-lactation
-heavy renal failure

# What are 3conditions in which calcium antagonists are the drugs of choice for hypertension:

+ elderly patients
+ obstructive pulmonary disease
+ metabolic syndrome
-appearing sodium retention
-first-trimester of pregnancy
-heart failure

# What are 3 conditions in which AT-1 blockers receptors are the drugs of choice for hypertension:

+ intolerant of ACE inhibitors
+ diabetes
+ renovascular hypertension
-pregnancy
-lactation
-arterialnaya hypertension in children

#Call 3 antihypertensive drugs used during pregnancy:

-lizinopril
+ verapamil
-lozartan
+metoprolol
+ alpha methyldopa
-gipotiazid

# Name rational drug combinations for the treatment of hypertension:

-beta-blockers + verapamil
-ingibitor ACE + K-sparing diuretics
+ calcium antagonist + ACE-inhibitors
+ diuretics + ACE-inhibitors
+ dihydropyridine calcium antagonists + beta-blocker
-alpha-blocker + calcium antagonist

# What are the 3drugs used for the treatment of systemic lupus erythematosus:

-levamizol
+ delagil
+D-penicillamine
+ cyclophosphamide or azathioprine
+ steroids
-colchicin

3 # Name of the drug used for treatment of dermatomyositis

+ steroids
- colchicin
-triamtsinolon
+ azathioprine
+ cyclophosphamide
-preparaty gold

# What are the side effects of loop diuretics:

+ hypokalemia, hyponatremia
-arterial hypertension
+ arrhythmias, hypotension
-gipourikemiya, hypercalcemia
+ hypomagnesemia, hypocalcemia
-stenokardiya, acidosis

# Name the drugs that cause acute drug-induced hepatitis:

+ tubazid
+ isoniazid
-ondansetron
+ paracetamol
-alfa- lipoic acid
- ademetionine

# The main side effects of statins:

-nefrotic syndrome
-blood diarrhea
+ cholestatic jaundice
+ cataracts
-deafness
+ myopathy, rhabdomyolysis

# Contraindications to the appointment of nitrates:

+ glaucoma
-porazhenie peripheral vascular
+ intracranial hypertension
-AV-Blockade
+ low systolic blood pressure
-disfunction left ventricle

# Specify the group of drugs used to treat coronary artery disease:

+ beta-blockers
+ lipid-lowering drugs
-diuretics
-alpha-blockers
+ antitrombotics
-spazmolitics

# Contraindications to the appointment of mannitol:

+ pulmonary edema
-otek brain
-glaucoma
+ brain hemorrhage
-lekarstvennaya intoxication
+ heart failure

# The cardiac effects of cardiac glycosides:

-positive dromotropic
+ positive inotropic
+ negative chronotropic
-negative bathmotropic
+ positive bathmotropic
-positive hronotropony

# Indications for heparin:

-aplastic anemia
+ treatment of atrial fibrillation
+ treatment of pulmonary embolism
-yazvennaya stomach trouble
+ treatment of arterial embolism
- aortic aneurysm

# Antibiotics prohibited for use at all stages of pregnancy:

+ quinolones
+ tetracyclines
+ streptomycin
-penitsilliny
-sefalosporines
-makrolidy

# Side effects specific to sulfonamides:

+ haematological disorders
+ crystalluria
+ dyspepsia
-violation view
-fotosensibilizatsiya
-diarrhea

# The drugs used in bacterial endocarditis:

+ vancomycin
+ penicillin
+ ampicillin
-levomitsetin
-tsiprofloksatsin
-linkomitsin

# Antibiotics having in its structure a beta-lactam ring:

+ penicillins
+ cephalosporins
+ carbapenems
-ftorquolons
-makrolid
-linkozamide