Dr lalji singh

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Centre for Cellular & Molecular Biology

Hyderabad 500007


FAX Telephones

International 91-40-27160252 or 27160591 Off: 040-27160789

India 040-27160252 or 27160591 Res: 040-27160555 or 27160556

CCMB Website: http://www.ccmb.res.in

E-mail: lalji@ccmb.res.in

Updated 21st April 2008

Father’s Name : Sri Surya Narain Singh
Date of Birth : 5th July 1947
Place of Birth : Jaunpur, Uttar Pradesh, India
Current Position & : DIRECTOR, CCMB, Hyderabad


Present : Centre for Cellular and Molecular Biology

Hyderabad 500 007 (A.P.)


Permanent : Village: Kalwari, Post Office: Sikrara,

District: Jaunpur, Uttar Pradesh, India

Educational Qualifications :
B.Sc. with Zoology, Botany and Chemistry, (1964),

M.Sc. in Zoology with thesis in Cytogenetics (1966)

Ph.D in Cytogenetics, 1971, Banaras Hindu University

(Thesis: Evolution of Karyotypes in Snakes)

Research Interests:

1. Molecular Basis of Sex-determination

2. DNA Fingerprinting

3. Wildlife Conservation

  1. Human Genome Analysis

5. Human Genetic Diversity
Dr Lalji Singh has more than 150 research papers published in internationally reputed journals.
Please see Annexure ‘D’ for complete list of Publications

Social Impact of some of the research work carried out by

Dr Lalji Singh

1. Development of a universal probe for DNA Fingerprinting:
Dr Lalji Singh and his colleagues at the Centre for Cellular & Molecular Biology (CCMB) developed a probe called Bkm-derived probe for DNA fingerprinting as a fallout of their earlier internationally well-known work on the mechanisms of the determination of sex. Their probe is being extensively used for forensic investigation, paternity determination and seed stock verification. DNA fingerprinting evidence was presented in the court and for the first time in the annals of the history of Indian Judiciary DNA fingerprinting was accepted as an infallible evidence in the court of law; this verdict was upheld by the Kerala High Court. Since then, they have used this indigenous technique in 500 cases such as paternity disputes, identification of missing children identification of mutilated bodies, exchange of babies in maternity wards and cases of rape and murder, etc. These include sensational cases of assassination of the late Prime Minister Shri Rajiv Gandhi, assassination of Punjab Chief Minister and the famous tandoor case of Naina Sahni.
DNA Fingerprinting technology has reached to common man all over India and is providing them a justice which otherwise would not have been possible for them to obtain.
Based on Dr Singh’s above findings a separate autonomous “Centre for DNA Fingerprinting and Diagnostics” has been set up by the Department of Biotechnology, Government of India.

2. Conservation of wildlife
Although our country is endowed with a tremendous wealth of megadiversity in plant and animal wildlife, their very existence is at stake owing to destruction of forests following industrialization, agricultural activities as well as poaching of wildlife for reasons of sports and money. There was therefore an urgent need to arrest this phenomena and work out strategies to tackle these problems by using innovative techniques. CCMB is, therefore, setting up a laboratory for the Conservation of Endangered Species (LaCONES) at Attapur village near Nehru Zoological Park. The potential utility of molecular techniques in the study of evolutionary relationships of plants and animals is already established. Dr Lalji Singh is presently using this technique for wild life preservation and better management of endangered species in our zoos and also for identification and isolation of genes for useful characters in silkworm races.

3. Species identification for forensic applications
Crimes related to the killing of animals are a serious threat in India. In such a case, we need to establish whether a drop of blood, or tiny piece of meat, bunch of hair or some other mutilated biological sample confiscated by the wildlife curators and/or investigating agencies belongs to human or animal, and if animal, to which species of animal. Such investigations have become very important in recent past with our increased awareness towards threats of extinction of many animal species due to human intervention. The law enforcement requires strong evidences in such matters which could be provided by establishing exact identity of confiscated animal(s) or parts and products thereof. The team of researchers headed by Dr Lalji Singh from the CCMB has recently developed, for the first time anywhere in the world, a novel DNA based approach which, without knowing the history of a forensic sample, is able to establish whether a drop of blood or tiny piece of meat belongs to human or animal, and if animal, to which species of the animal. CCMB has already using this approach in providing the service to the society and has resolved more than 50 cases forwarded by various wildlife curators and crime investigation agencies.

4. DNA based molecular Diagnostics
There are several genetic disorders prevalent in our country. The problem has become much more serious because there are no adequate facilities for diagnosing these disorders. Dr Lalji Singh and his group have set up diagnostic services for many genetic disorders such as sickle cell anemia, Alzheimer’s disease, BCD, male infertility, pancreatitis, Robert’s syndrome, etc. Research by Dr Lalji Singh and his colleagues further helped in better understanding of the role played by genetic factors in these diseases and the possibility of developing better diagnostic tools for the detection and the management of such diseases. These services will be of tremendous help to common man in reducing their agonies whenever therapeutic intervention is possible.

5. Genetic affinities of Andaman Islanders
Dr Lalji Singh and his group have undertaken the study on genetic diversity in primitive tribes of India including the tribal populations of Andaman and Nicobar Islands using Y-chromosomal markers and mtDNA sequences. Data indicates that the Andamanese have closer affinities to Asian than to African population and suggests that they are the descendants of the early Paleolithic colonizers of Southeast Asia – the hunter gatherers and the first migrants moved out of Africa about 60,000-100,000 years ago. These findings have revolutionized the ways of thinking about the origin of man in terms of their evolution and migration from place to place.

6. Genome Foundation and its activities

Human disease and suffering are as old as humanity and genetic disorders are most distressing since there is no cure available for them and the diseases get transmitted across the generations. The problem of genetic disorders in India is enormous. Indians are also genetically susceptible to common diseases, such as, diabetes and heart diseases. Thus, prevention of disability is the only option for these disorders. However, the diagnostic services for them are mostly focused to cater the urban India.
A group of intellectuals with high professional integrity have come together to establish this Foundation under Dr Lalji Singh as its Managing Director, which will provide such diagnostic services to both rural and urban populations of the country. The Foundation will function with people’s participation and utilize the voluntary services of retired scientists and professionals. The Foundation will establish various centres across the length and breadth of India to take these services to the masses through networking with various NGOs and socially committed organizations. The Foundation is already registered under Section 25 of the Companies Act, 1956. A Foundation stone was laid recently by Dr Lalji Singh for a building complex for “Establishing a Rural Centre of Genome Foundation in Northern India” in Jaunpur, UP, India.

Annexures: A. Honours, Awards and Endowment Lectures

  1. Academic and Service Affiliations

  2. Research Interests

  3. List of Publications

  4. List of Patents and Popular Articles

  5. Information on and Relevance of Research Contributions

G. Teaching Experience

H. Organisation of Courses

I. Administrative Experience

J. Sponsored Research/Collaborations

K. International meetings attended

L. Membership of Professional Societies

M. Fellowship of Indian/Foreign Academies

N. Membership of Editorial Boards

O. Membership of Professional Committees



2nd University Foundation Oration

KLE University, Belgaum


18th Convocation of Kakatiya University

Kakatiya University, Warangal (A.P.)


8th Dharma Vira Oration

Sir Gangaram Hospital, New Delhi


Rajbhasha Shri Samman by Bharatiya Rajbhasha Vikas Sansthan



Rashtriya Ekta Samman 2007

National Unity Conference, New Delhi


Sir Edward Mellanby Memorial Lecture

Central Drug Research Institute, Lucknow


Honorary D.Sc. degree

Deendayal Upadhyay Gorakhpur University, Gorakhpur


Dr L D Sanghvi Oration Award

Indian Society of Human Genetics


Father of DNA Fingerprinting Award

Jaunpur Journalists Assocation


J C Bose National Fellowship

Department of Science & Technology


Honorary D.Sc. degree

Uttar Pradesh Rajarshi Tandon Open University, Allahabad


Honorary Professor

Sri Venkateswara University, Tirupati


ISWA Honorary Fellowship (2005)

Indian Science Writers’ Association (ISWA)


Honorary Fellow, Biotech Research Society of India

Biotech Research Society of India


Swami Sukhdevanand Rishi Samman in the field of Genetics

Mumukshu Ashram Siksha Sankul, Shahjahanpur


Intellectuals’ Honour – The Great Son of the Soil

All India Conference of Intellectuals, Meerut


Honorary D.Sc. degree

Banaras Hindu University, Varanasi


Awarded Padma Shri by the President

Government of India


FICCI Award 2002-03 for R&D in Life Sciences

Federation of Indian Chambers of Commerce and Industry, New Delhi.


Biotechnologist of the year 2002

Metro Vision Business & Technology Magazine, Hyderabad


Vigyan Gaurav Award

Council of Science & Technology, Government of Uttar Pradesh


The Honorary D.Sc. degree

Mahatma Gandhi Kashi Vidyapeeth, Varanasi


Purvanchal Ratna

Veer Bahadur Singh Poorvanchal University, Jaunpur



Indian Society of Health Environment Education and Research (ISHEER), Jodhpur Centre, Jodhpur


TWAS Fellowship

Third World Academy of Sciences Trieste, Italy


Sixth Prof. S. P. Ray-Chaudhuri Memorial Lecture Award

Prof. S. P. Ray-Chaudhuri Foundation, BHU, Varanasi


New Millennium Plaques of Honour - 2001-2002 award for outstanding services in the field of Biological Sciences

By the Prime Minister of India at the 89th Session of the Indian Science Congress-2002


K N Bhal Memorial Gold Medal for 2001

Society of Biosciences, Muzaffarnagar


The D.A.E. – C.V. RAMAN Lecturership-2000

Indian Physics Association, Mumbai


Goyal Prize in Life Sciences-2000

Kurukshetra University, Haryana


CRI Foundation Day Oration Lecture

Cancer Research Foundation, Mumabi


Late Sri Damodaram Sanjivayya Endowment Lecture

Sri Venkateswara University, Tirupati


Dr Y Nayudamma Memorial Extension Lecture on Biotechnology-1999

Dr Y Nayudamma Memorial Turst, Tenali


Kothari Memorial Endowment Lecture

Pondicherry University,



Visesha Puraskaaram

Dr Ramineni Foundation, USA


The Honorary D.Sc., degree

Purvanchal University, Jaunpur, U.P.



Andhra Pradesh Akademi of Sciences, Hyderabad


IMTECH Foundation Day Lecture

Institute of Microbial Technology, Chandigarh


II Mansi Ram Memorial Lecture

University of Delhi, Delhi


Professional Excellence Award in Science & Technology - for Expertise in DNA Fingerprinting

Viswabharathy Academy, Hyderabad


IV Endowment Lecture

The Indian Instrumentation Society, Hyderabad Chapter, Hyderabad


Scroll of Honour: Outstanding Forensic Expert Award - for Indianization of DNA Fingerprinting Technology

The Medico Legal Society, All India Institute of Medical Sciences, New Delhi.


Honorary Professor

School of Animal Sciences, University of Hyderabad, Hyderabad


Indian Academy of Neurology Oration

Indian Academy of Neurology, Bangalore


Dr Yellapragada Subbarow Memorial Oration

The Indian Medical Association, Vijayawada


Joy Govind Law Memorial Medal

The Asiatic Society, Calcutta


Padma Bhushan Dr P S Siva Reddy Endowment Award

Dr P Siva Reddy Founda-tion, Hyderabad


Shri Om Prakash Bhasin Award – in the field of Biotechnology

Shri Om Prakash Bhasin Foundation for Science & Technology, Delhi


Haldane Oration Medal

Society for Bionaturalists, India


The VASVIK Research Award – for Biological Sciences & Technology for the year 1992

Vividhlaxi Audyogik Samshodhan Vikas Kendra, Bombay


Professor Vishwanath Memorial Lecture Award

Indian National Science Academy, New Delhi.


Jagdish Chandra Bose Award – for Research in Life Sciences

Hari Om Ashram Trust, Delhi


Ranbaxy Research Award – in the field of basic medical sciences

Ranbaxy Research Foundation, Ranbaxy, New Delhi


Prof S P Ray-Chaudhuri 75th Birthday Endowment Lecture Award

Banaras Hindu University, Varanasi


CSIR Technology Award – for biological sciences

Council of Scientific & Industrial Research, New Delhi



Commonwealth Scholarship – for Postdoctoral Research in Molecular Biology

Edinburgh University, UK


INSA Medal for Young Scientists

Indian National Science Academy, New Delhi


Dr S P Basu Memorial Medical - for outstanding contribution in the field of Cytogenetics

Zoological Society, Calcutta


Banaras Hindu University Gold Medal – for standing first in order of merit in M.Sc (Zoology)

Banaras Hindu University, Varanasi

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