Traditional Posters: Body Imaging

Gregory James Wilson^1,2, George R. Oliveira², Jeffrey Harold Maki, <sup>2,3

1</sup>MR Clinical Science, Philips Healthcare, Cleveland, OH, United States; ²Radiology, University of Washington, Seattle, WA, United States; ³Radiology, Puget Sound VA HCS, Seattle, WA, United States

Black-blood (BB) T2-weighted (T2w) imaging can provide increased liver lesion conspicuity over standard bright-blood T2w imaging. The sequence evaluated here uses respiratory navigator-triggering and a motion-sensitized driven equilibrium (MSDE) pre-pulse with a multi-slice turbo spin echo (TSE) readout. This sequence provides BB T2w images with high TSE image quality and without EPI distortions. In this study, various motion-sensitizing gradient directions and strengths were evaluated.

2616. Single Breath-Hold High Spatial Resolution Abdominal Imaging and T2* Mapping at 7.0 T

Matthias Alexander Dieringer^1,2, Fabian Hezel¹, Wolfgang Renz, ^1,3, Philipp Boyé, ¹², Bernd Ittermann, ^1,4, Frank Seifert, ^1,4, Tomasz Lindel, ^1,4, Thoralf Niendorf<sup>1,2

1</sup>Berlin Ultrahigh Field Facility, Max-Delbrueck-Center for Molecular Medicine, Berlin, Germany; ²Experimental and Clinical Research Center (ECRC), Charité Campus Buch, Humboldt-University, Berlin, Germany; ³Siemens Healthcare, Erlangen, Germany; ⁴Physikalisch-Technische Bundesanstalt (PTB), Berlin, Germany

Abdominal imaging examinations constitute a growing fraction of clinical MRI exams. Since ultrahigh field magnetic resonance imaging becomes more widespread, a range of applications established in the clinical scenario at 1.5 T and 3.0 T is emerging at 7.0 T. An eight channel transceiver surface coil array together with a 2D fast gradient echo sequence delivered high details of abdominal sub-millimeter anatomic structures, such as the gallbladder wall and subtle liver vessels without the application of contrast agent, and enabled T2*-Mapping of the liver at 7.0 T.

2617. MR Imaging of the Human Biliary Tree Using a Flexible Catheter-Mounted Radio-Frequency Detector Microcoil

Christopher Antony Wadsworth¹, Shahid A. Khan¹, Simon D. Taylor-Robinson¹, Wladyslaw M W Gedroyc², Munir M. Ahmad³, Richard R. A. Syms³, Ian R. Young<sup>3

1</sup>Department of Hepatology & Gastroenterology, Imperial College, London, United Kingdom; ²MRI Unit, Imperial College Healthcare NHS Trust, London, United Kingdom; ³Department of Electrical and Electronic Engineering, Imperial College, London, United Kingdom

Problem: Strictures in the biliary tree are difficult to characterise as benign or malignant. A RF receiver microcoil applied directly to the biliary tree should improve MRI resolution substantially. Method: An innovative flexible catheter mounted microcoil has been developed. This was used as the receiver coil in MR imaging of a resected liver and biliary tree. Results: High resolution images were obtained. Signal to noise ratios and resolution were substantially better with the microcoil than with the standard coil. Conclusion: A prototype RF microcoil receiver can produce high quality images of ex vivo human liver tissue. These images demonstrate interpretable anatomical detail with sub-millimetre resolution and are superior to those obtained using a standard body coil.

2618. High Spatial and Temporal Resolution Perfusion Imaging of Hepatocellular Carcinoma with Time-Resolved 3DPR Using a 32-Channel Coil at 3T

Ethan K. Brodsky^1,2, Walter F. Block^2,3, William Schelman^4,5, Scott B. Reeder<sup>1,2

1</sup>Radiology, University of Wisconsin, Madison, WI, United States; ²Medical Physics, University of Wisconsin, Madison, WI, United States; ³Biomedical Engineering, University of Wisconsin, Madison, WI, United States; ⁴Carbone Cancer Center, University of Wisconsin, Madison, WI, United States; ⁵Medicine, University of Wisconsin, Madison, WI, United States

Detection, characterization, and monitoring of hepatocellular carcinoma (HCC) is challenging due to its variable and rapid arterial enhancement. The ability to monitor changes in both morphology and perfusion is essential for evaluating the effectiveness of anti-angiogenic therapies. Multiple-phase CE-MRI has traditionally been used, but suffers from limited temporal resolution and an inability to consistently match acquisitions to the desired enhancement phase. We demonstrate the feasibility of contrast-enhanced isotropic-resolution 3DPR acquisition at 3T using a 32-channel coil with real-time monitoring that allows breath-holds to be matched to the desired enhancement phase and enables retrospective selection of the temporal window showing optimal lesion contrast.

2619. Contrast Uptake Enhancement Patterns in Neuroendocrine Liver Metastases

Choon Hua Thng¹, Tong San Koh², Septian Hartono¹, Puor Sherng Lee¹, Keiko Miyazaki³, David Collins³, Martin O. Leach³, Val Lewington⁴, Dow-Mu Koh<sup>4

1</sup>National Cancer Centre Singapore, Singapore, Singapore; ²Nanyang Technological University, Singapore, Singapore; ³CRUK-EPSRC Cancer Imaging Centre, Institute of Cancer Research, Sutton, United Kingdom; ⁴Royal Marsden NHS Foundation Trust, Sutton, United Kingdom

Neuroendocrine liver metastases have been described as being hypervascular in nature, showing arterial enhancement and washout. However, other enhancement patterns have been observed in clinical practice (plateau and progressive enhancement). Three types of enhancement curves in neuroendocrine tumor was found: (1) Rapid increasing followed by decrease, (2) Rapid increasing followed by plateau, and (3) Progressively increasing. Type I pattern show higher intravascular volume (v1) compared to percentage of interstitial volume (v2). Type II and III pattern show higher v2 compared to v1. Type I pattern show higher blood flow (F) compared to Type II/III.

2620. Clinical Experience with Gadoxetate-Enhanced T1 Weighted Hepatobiliary Imaging in Primary Sclerosing Cholangitis