Traditional Posters: Body Imaging



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Michal Marianne Amitai1, Miriam stern2, Marjory Hertz3, Yacov Itzchak3, yael Inbar3, Sara Apter3

1Diagnostic Imaging, Sheba Medical Center, Ramat Gan, Israel, Israel; 2Diagnostic Imaging, Sheba Medical Center,, Ramat Gan, Israel,, Israel; 3Diagnostic Imaging, Sheba Medical Center, Ramat Gan, Israel, Israel

Purpose: To evaluate the impact of MRI of the abdomen and pelvis in pregnant women on clinical and obstetrical management. Methods: Thirty one consecutive MRI studies of the abdomen of 29 pregnant patients, were included in the study Correlation between the MRI pathological findings related to the stage of pregnancy and the clinical and obstetric outcome were evaluated. Results: The indications for studies included: gynecologic conditions (9), suspected Crohn disease (7), suspected appendicitis (6), cancer staging and follow up (5), postoperative complications (3) and suspected pheochromocytoma (1). Conclusions: MR imaging proved to be appropriate in the management of pregnant patients with diverse abdominal pathology and could provide an accurate diagnosis prior to delivery in all patients.



2664. The Effect of Maternal Smoking on Fetal Lung and Kidney Growth

Devasuda Anblagan1, Carolyn Costigan2, Tomas Paus2, Zdenka Pausova2, Nia Wyn Jones3, George Bugg3, Nick Raine Fenning4, Penny Anne Gowland1

1Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom; 2Brain and Body Centre, University of Nottingham, United Kingdom; 3Queen's Medical Centre, University of Nottingham, United Kingdom; 4Division of Human Development, School of Clinical Sciences, University of Nottingham, United Kingdom

This study aims to identify the effect of maternal smoking during pregnancy on fetal lung and kidney growth. Pregnant women were scanned at 24th to 26th weeks and 34 to 36 weeks postconception. The lung and kidney MR images were analysed using semi automatic approach with Analyze software. Fetal lung and kidney volumes were reduced in the smoker group.



2665. Reliability Test for Fetal Fat Programme

Devasuda Anblagan1, Carolyn Costigan2, Alain Pitiot3, Tomas Paus2, Zdenka Pausova2, Nia Wyn Jones4, George Bugg4, Ruta Deshpande4, Mona S. Moghazy A. Salmam4, Penny Anne Gowland1

1Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom; 2Brain and Body Centre, University of Nottingham, United Kingdom; 3School of Psychology, University of Nottingham, United Kingdom; 4Queen's Medical Centre, University of Nottingham, United Kingdom

This study aims to investigate the reliability of a MATLAB program designed to calculate the subcutaneous fat volume in the fetus. It will be employed in a study investigating macrosomia outcomes in diabetic pregnant mothers. The MR technique used to assess the foetal growth is Fat Sequences with Water Suppression where pregnant women were scanned in late pregnancy (after 30th gestation week) when fetal fat is more visible.



2666. Impact of Anti-Inflammatory Treatment on Placental and Neurodevelopmental Defects Monitored in Utero by MRI

Sylvie Girard1, Luc Tremblay2, Guillaume Sebire1, Martin Lepage2

1Pediatric, Universite de Sherbrooke, Sherbrooke, Qc, Canada; 2Radiobiology, Universite de Sherbrooke, Sherbrooke, Qc, Canada

Perinatal inflammation predominantly affects preterm newborns leading to brain damage. Interleukin-1 (pro-inflammatory molecule) appears to be a key mediator linking maternal inflammation and fetal brain damage. Strategies to protect the fetal brain are currently unavailable mainly due to the lack of non-invasive tools to detect in utero inflammation and monitor the impact of an anti-inflammatory treatment. We showed that MRI is a potent technique to detect placental damage and can be used to monitor the impact of anti-inflammatory treatment in an animal model of prenatal inflammation.



2667. Assessment of Placental Morphology and Magnetic Resonance Imaging Biomarkers at 1.5 Tesla

David M. Morris1,2, Caroline Wright3, Philip N. Baker4, Ian P. Crocker3, Penny A. Gowland5, Geoff J. Parker1,2, Colin P. Sibley3

1Imaging Science and Biomedical Engineering, School of Cancer and Imaging Sciences, University of Manchester, Manchester, United Kingdom; 2The University of Manchester Biomedical Imaging Insitute, University of Manchester, Manchester, United Kingdom; 3Maternal & Fetal Health Research Centre, University of Manchester, Manchester, United Kingdom; 4Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Canada; 5Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, United Kingdom

Fetal growth retardation (FGR) is a serious condition affecting babies in utero that can be identified by means of a placental phenotype related to structural and functional changes in the placenta. Magnetic resonance imaging (MRI) measured the relaxation times T1 and T2 as possible biomarkers of this condition and placentas were collected for the histological verification of FGR pathology. We show for the first time that both in utero T1 and T2 demonstrate a significant negative correlation with the gestational age at 1.5 T and that relaxation times correlate with histological biomarkers of placental development.



2668. T1-Weighted Imaging of Fetal Microcolon


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