Traditional Posters: Body Imaging

Nathan S. Artz¹, Kevin Johnson¹, Yin Huang¹, Elizabeth A. Sadowski², Sean B. Fain<sup>1,2

1</sup>Medical Physics, University of Wisconsin-Madison, Madison, WI, United States; ²Radiology, University of Wisconsin-Madison, Madison, WI, United States

Quantifying arterial spin labeling (ASL) perfusion measurements using data acquired at only one delay time requires assumptions for quantification that may be invalid, especially in diseased kidneys which may demonstrate a wide variety of blood flows. The purpose of this study was to demonstrate the feasibility of efficiently acquiring data at multiple delay times using a radial balanced SSFP approach. ASL-FAIR was performed in a healthy volunteer at 1.5 T during which unique radial projections were continually acquired from 0.2 to 2 seconds following inversion. Twenty delay time images were acquired over 11 minutes. The control and tag images show reasonable image clarity and the difference images clearly demonstrate perfusion however streaking is originating from below the left kidney (right side). Future work will focus on reducing the streak artifact using motion compensation techniques and/or optimizing k-space trajectories.

2681. A Prospective Study Following Patients with Chronic Kidney Disease Undergoing Contrast-Enhanced MRI

Matthew J. Kuhn¹, Bryce K. Young¹, N S. Mamillapalli², Kalyani Vallurupalli<sup>3

1</sup>Radiology, University of Illinois at Peoria, Peoria, IL, United States; ²Radiology, Southern Illinois University, Springfield, Ilinois, United States; ³Radiology, Southern Illinois University, Springfield, IL, United States

As part of an ongoing prospective multicenter study to determine the incidence of NSF in patients with stages 3 to 5 chronic kidney disease (CKD) undergoing magnetic resonance imaging (MRI) of the central nervous system with gadobenate dimeglumine, 223 patients have been enrolled at 15 sites. Patients are followed for 2 years with a regular schedule of telephone calls and visits. To date, no case of NSF has been reported, although follow-up is ongoing in most of these patients.

2682. Low-Dose Contrast-Enhanced Time-Resolved Renal MRA

Hyun Jong Jeong¹, James C. Carr², Timothy J. Carroll<sup>1,2

1</sup>Biomedical Engineering, Northwestern University, Chicago, IL, United States; ²Radiology, Northwestern University, Chicago, IL, United States

Dynamic imaging of the kidneys using MR offers non-invasive information about the renal anatomy and function. However, despite many improvements in renal MRA, there is a need for higher temporal resolution in time-resolved MRA, while minimizing the risks associated with gadolinium based contrast agents. In this study, low-dose renal MRA was performed using the previously developed CAMERA technique to achieve higher temporal resolution without undersampling.

2683. PME Dynamics of Pig's Kidney During Oxygenated Hypothermic Pulsatile (HPP) Compared to Cold Static Storage (CSS)

Francois Lazeyras^1,2, Leo Buhler³, Antonio Nastasi³, Raphael Ruttimann³, Philippe Morel³, Jean-Bernard Buchs<sup>3

1</sup>Service of Radiology, University of Geneva and University Hospital of Geneva, Geneva, Switzerland; ²Center for Biomedical Imaging (CIBM), Lausanne and Geneva, Switzerland; ³Visceral and Transplantation Service, University of Geneva and University Hospital of Geneva, Geneva, Switzerland

In this study, we compare 2 cold storage conditions for transplantation using 31P CSI: Oxygenated pulsatile perfusion (O2+HPP) performed immediately after kidney harvesting vs. simple cold storage (CSS). We found that ATP did not fully recovered after 8 hours of CSS, and PME/Pi time constant was similar in both conditions (~0.05 h-1). Assessment of PME and ATP kinetics are important in the context of organ evaluation before transplantation as they may be considered as markers of kidney’s viability.

2684. Measuring Glomerular Protein Leakage with Dual-Agent DCE-MRI: Reproducibility in Healthy Pigs