Electronic Posters: Cardiovascular

Thursday 13:30-15:30 Computer 30

13:30 3596. Clinical Cardiac Imaging at 7 Tesla: A Validation Study.

Joseph J. Suttie¹, Lance DelaBarre², Greg J. Metzger², Pierre Francois van de Moortele², Carl J. Snyder², Peter Weale³, Stefan Neubauer¹, Matthew D. Robson¹, J Thomas Vaughan<sup>2

1</sup>Department of Cardiovascular Medicine, University of Oxford, Oxford Centre for Clinical Magnetic Resonance Research, Headington, Oxfordshire, United Kingdom; ²University of Minnesota, Radiology Center for Magnetic Resonance Research, Minneapolis, MN, United States; ³Cardiovascular MR Research and Development, Siemens Healthcare, Chicago, IL, United States

Clinical cardiac imaging at 7 T is attractive for spectroscopy, coronary and perfusion imaging. It offers improved signal and contrast to noise, provided technical challenges of ECG and artifacts can be overcome. This study compares SSFP and FLASH imaging at different field strengths: 1.5, 3 and 7 Tesla.

14:00 3597. Quantifying Right Ventricular Motion and Deformation Using 3D Cine DENSE MRI

Daniel Alejandro Auger¹, Xiaodong Zhong², Ernesta Meintjes¹, Fred Epstein³, Bruce Spottiswoode<sup>1,4

1</sup>MRC/UCT Medical Imaging Research Unit, University of Cape Town, Cape Town, Western Cape, South Africa; ²MR R&D Collaborations, Siemens Medical Solutions, Atlanta, GA, United States; ³3Departments of Radiology and Biomedical Engineering, University of Virginia, , Charlottesville VA, United States; ⁴Radiology, University of Stellenbosch, Cape Town, South Africa.

Displacement encoding with stimulated echoes (DENSE) is a quantitative MRI technique used for measuring myocardial displacement and strain at a high spatial resolution. Studies quantifying the motion of the right ventricle (RV) have been limited by the RV’s thin wall, asymmetric geometry and complex motion. A free-breathing navigator gated spiral 3D cine DENSE sequence has recently been developed, thus providing a well suited tool for capturing the complex behavior of the RV. This study involves analyzing the RV’s 3D motion and strain at a previously unattainable spatial resolution. The results are consistent with previous studies using myocardial tagging.

14:30 3598. Diffusion Tensor Imaging of Healthy and Cryo-Injured Pig Hearts

Patricia Dreessen de Gervai¹, Victor Yang, Uta Sboto-Frankenstein, Valery Kupriyanov, Lawrence Ryner

¹National Research Council Institute for Biodiagnostics, Winnipeg, Manitoba, Canada

Diffusion Tensor Magnetic Resonance Imaging (DTI) was used to assess myocardial architecture in healthy and in injured excised pig hearts in which cryo-ablation was used to produce targeted infarctions. Using the lesion and penumbral region as seed points, fibers were not detectable in the infarct region, FA was reduced and ADC values increased compared to healthy excised hearts. The penumbral region contained traceable fibers although FA and ADC values were affected. This work suggests that the changes in fiber architecture, FA and ADC involve not only the infarct area but also the adjacent tissue.

15:00 3599. Retrospective Self-Gated Free-Breathing Radial 3D Cine SSFP CMR Using Self-Calibrated GRAPPA: A Feasibility Study

Noel C. Codella¹, Pascal Spincemaille², Jing Liu², Martin Prince², Yi Wang<sup>2

1</sup>Physiology, Cornell Weill Medical College, New York, NY, United States; ²Radiology, Cornell Weill Medical College

In this study, a 3D free-breathing self-calibrated radial GRAPPA cine-SSFP pulse sequence was developed to overcome the limitations of 2D breath-hold imaging. Radial k-space sampling was employed to provide z-profile self-navigator to monitor respiratory motion, and to allow for GRAPPA self-calibration.