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A novel Pfs38 protein complex on the surface of Plasmodium falciparum blood-stage merozoites



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A novel Pfs38 protein complex on the surface of Plasmodium falciparum blood-stage merozoites


The Plasmodium genome encodes for a number of 6-Cys proteins that contain a module of six cysteine residues forming three intramolecular disulphide bonds. These proteins have been well characterized at transmissi...

Gourab Paul, Arunaditya Deshmukh, Inderjeet Kaur, Sumit Rathore, Surbhi Dabral, Ashutosh Panda, Susheel Kumar Singh, Asif Mohmmed, Michael Theisen and Pawan Malhotra

Malaria Journal 2017 16:79

WHO cone bio-assays of classical and new-generation long-lasting insecticidal nets call for innovative insecticides targeting the knock-down resistance mechanism in Benin


To increase the effectiveness of insecticide-treated nets (ITN) in areas of high resistance, new long-lasting insecticidal nets (LLINs) called new-generation nets have been developed. These nets are treated wi...

Marius Allossogbe, Virgile Gnanguenon, Boulais Yovogan, Bruno Akinro, Rodrigue Anagonou, Fiacre Agossa, André Houtoukpe, Germain Gil Padonou and Martin Akogbeto

Malaria Journal 2017 16:77

Alternative transmission routes in the malaria elimination era: an overview of transfusion-transmitted malaria in the Americas


Transfusion-transmitted (TT) malaria is an alternative infection route that has gained little attention from authorities, despite representing a life-threatening condition. There has been no systematic review ...

Regina M. Alho, Kim Vinícius Amaral Machado, Fernando F. A. Val, Nelson A. Fraiji, Marcia A. A. Alexandre, Gisely C. Melo, Judith Recht, André M. Siqueira, Wuelton M. Monteiro and Marcus V. G. Lacerda

Malaria Journal 2017 16:78

Molecular evidence of Plasmodium vivax infection in Duffy negative symptomatic individuals from Dschang, West Cameroon


Plasmodium vivax infection is known to be rare in West/Central Africa, the most accepted explanation being the lack of expression of erythroid Duffy antigen in the local human populati...

Gianluca Russo, Giovanni Faggioni, Giacomo Maria Paganotti, Ghyslaine Bruna Djeunang Dongho, Alice Pomponi, Riccardo De Santis, Gianpiero Tebano, Mpoame Mbida, Martin Sanou Sobze, Vincenzo Vullo, Giovanni Rezza and Florigio Romano Lista

Malaria Journal 2017 16:74

Community engagement and the social context of targeted malaria treatment: a qualitative study in Kayin (Karen) State, Myanmar


The spread of artemisinin-resistance in Plasmodium falciparum is a threat to current global malaria control initiatives. Targeted malaria treatment (TMT), which combines mass anti-malarial administration with con...

Kate Sahan, Christopher Pell, Frank Smithuis, Aung Kyaw Phyo, Sai Maung Maung, Chanida Indrasuta, Arjen M. Dondorp, Nicholas J. White, Nicholas P. J. Day, Lorenz von Seidlein and Phaik Yeong Cheah

Malaria Journal 2017 16:75

The effect of elevated temperatures on the life history and insecticide resistance phenotype of the major malaria vector Anopheles arabiensis (Diptera: Culicidae)


Temperature plays a crucial role in the life history of insects. Recent climate change research has highlighted the importance of elevated temperature on malaria vector distribution. This study aims to examine...

Shüné V. Oliver and Basil D. Brooke

Malaria Journal 2017 16:73

Referral of children seeking care at private health facilities in Uganda


In Uganda, referral of sick children seeking care at public health facilities is poor and widely reported. However, studies focusing on the private health sector are scanty. The main objective of this study wa...

Anthony K. Mbonye, Esther Buregyeya, Elizeus Rutebemberwa, Siân E. Clarke, Sham Lal, Kristian S. Hansen, Pascal Magnussen and Philip LaRussa

Malaria Journal 2017 16:76

Analysing trends and forecasting malaria epidemics in Madagascar using a sentinel surveillance network: a web-based application


The use of a malaria early warning system (MEWS) to trigger prompt public health interventions is a key step in adding value to the epidemiological data routinely collected by sentinel surveillance systems.

Florian Girond, Laurence Randrianasolo, Lea Randriamampionona, Fanjasoa Rakotomanana, Milijaona Randrianarivelojosia, Maherisoa Ratsitorahina, Télesphore Yao Brou, Vincent Herbreteau, Morgan Mangeas, Sixte Zigiumugabe, Judith Hedje, Christophe Rogier and Patrice Piola

Malaria Journal 2017 16:72

Cellulose filtration of blood from malaria patients for improving ex vivo growth of Plasmodium falciparum parasites


Establishing in vitro Plasmodium falciparum culture lines from patient parasite isolates can offer deeper understanding of geographic variations of drug sensitivity and mechanisms of malaria pathogenesis and imm...

Sixbert I. Mkumbaye, Daniel T. R. Minja, Jakob S. Jespersen, Michael Alifrangis, Reginald A. Kavishe, Steven B. Mwakalinga, John P. Lusingu, Thor G. Theander, Thomas Lavstsen and Christian W. Wang

Malaria Journal 2017 16:69

Avidity of anti-malarial antibodies inversely related to transmission intensity at three sites in Uganda


People living in malaria endemic areas acquire protection from severe malaria quickly, but protection from clinical disease and control of parasitaemia is acquired only after many years of repeated infections....

Isaac Ssewanyana, Emmanuel Arinaitwe, Joaniter I. Nankabirwa, Adoke Yeka, Richard Sullivan, Moses R. Kamya, Philip J. Rosenthal, Grant Dorsey, Harriet Mayanja-Kizza, Chris Drakeley, Bryan Greenhouse and Kevin K. A. Tetteh

Malaria Journal 2017 16:67

New potential Plasmodium brasilianum hosts: tamarin and marmoset monkeys (family Callitrichidae)


Non-human primates (NHPs) as a source for Plasmodium infections in humans are a challenge for malaria elimination. In Brazil, two species of Plasmodium have been described infecting NHPs, Plasmodium brasilianum a...

Denise A. M. Alvarenga, Anielle Pina-Costa, Cesare Bianco, Silvia B. Moreira, Patricia Brasil, Alcides Pissinatti, Claudio T. Daniel-Ribeiro and Cristiana F. A. Brito

Malaria Journal 2017 16:71


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