From: "Paul Heelis" Subject: New chemistry jobs vacancy site To

Date: Wed, 31 May 2000 19:09:42 +0200

From: [e-mail]

Subject: ORGLIST: Phosphatidyl choline derivatives
Dear Colleagues,

I'm trying to carry out the synthesis of a modified phosphatidylcholine by

reacting the sodium salt ofphosphatidic acid with a "bidentate" choline

analog (bromine salt)

(HO-CH2-CH2-N(CH3)2-CH2-CH2-S-S-CH2-CH2-N(CH3)2-CH2CH2OH).

As you can see, in our intention, the result would be the attachment of two

phosphatidyl residues to this "choline".

I'm trying the reaction with the usual chemical method, that is, the

reaction with triisopropylbenzenesulfonyl chloride in dry piridine, but it

doesn't work.

Could anyone suggest me any simpler ways to carry out this transformation,

or some hints to improve this "old" procedure?

Thanks in advance
Andrea D'Annibale

Dipartimento di Chimica,

Universita' degli Studi "La Sapienza",

P.le Aldo Moro 5, 00185 Roma, ITALIA

tel: [phone]

fax: [phone]

e-mail: [e-mail]

__________________

Date: Wed, 31 May 2000 22:56:57 +0200

From: Shu-Kun Lin

Organization: MDPI (http://www.mdpi.org)

Subject: Re: ORGLIST: Information - Revolution?
Hi,
You may try both http://www.molmall.org and http://www.molbank.org.

They are installed by the very smart chemist, my colleague Dr. Luc Patiny,

Institute of Organic Chemistry, University Lausanne, ICO-BCH,

1015 Lausanne, Switzerland e-mail [e-mail].

Both have substructure search function. You can draw structure

using the Java on the internet. Dr. Jacob Zabicky mentioned that

he would like to contribute substances. If we did not reply, please

excuse us. Now there are two full time Ph.D. chemists working for

MDPI Center in Basel, Switzerland. We are improving our service.
Shu-Kun
--

Dr. Shu-Kun Lin

Molecular Diversity Preservation International (MDPI)

Saengergasse 25, CH-4054 Basel, Switzerland

Tel. [phone], Fax [phone]

E-mail: [e-mail]

http://www.mdpi.org/lin/
Jacob Zabicky wrote:

>

> Dear friends,

>

> The points of the scientists and educators have amply been made in the

> present threadline. At a risk of being a dissonant voice, let me remind you

> there are other aspects to consider, some of which were alredy touched,

> however scantly.

>

> 1. Publishers are there to make a profit, Yes, we say, but profit should be

> a "reasonable" one. Let's not forget that's not the way a free market

> works. They'll keep on charging whatever they want unless somebody stops

> them. The only one to stop them is the buyer by haggling, threatening and

> actually cancelling subscriptions. The latter may really be frightening to

> publishers, because the costs of production are much higher than those of

> reproduction (i.e., printing).

>

> 2. Production costs of certain scientific publications are high, however,

> today there are many ways of substantially reducing them, without affecting

> the quality of the contents or presentation. None of these ways will be

> mentioned, but publishers know them well. They are not implemented because

> that requires certain changes of editorial policies, and there's no urge

> because libraries buy the stuff anyway.

>

> 3. Certain publications are oriented towards industry, however, university

> libraries can do good use of the information therein. You can subscribe

> only at outrageus prices. In fact, industy pays only a fraction of that

> price, as the subscription is tax deductable, possibly in more than one

> way; no such deduction is applicable to universities as nonprofit

> organizations. Unless industry revolts against such overpricing there's

> little universities can do about it.

>

> 4. The "free" enterprises like the one mentioned by Dr. Shu-Kun Lin (see

> below) do not always work so smoothly, possibly due to their limited

> capacipty for handling everything on a restricted budget. For example, I

> gave it up after addressing several times Dr. Shu-Kun Lin with quetions

> relevant to the substances I wanted to send to the MolBank, and getting no

> reply. You don't pay and there isn't realy anything to demand from a

> good-will organization. On the other hand, if you pay there are potentially

> some resources in case your expectations are not satisfied; that's the

> stuff other specialists live of.

>

> All he best,

>

> Jacob Zabicky

__________________

JUNE 2000

Date: Thu, 1 Jun 2000 15:42:05 +0900

From: "Michael Engel"

Subject: ORGLIST: preprint & publication
Hello
When I am reading about preprint servers, I am wondering about the actual

procedure.

In the timescale of a publication, when will it be send to such a server.

Before you send it to a journal ? They will not accept my paper then -

already published.

After sending it to a journal - I will not be allowed because of the reduced

revenue for the publisher. Some people will download the preprint, as it

contains the same data. Or will the preprint be erased after publication ?

Thanks for any enlightenment.
Michael Engel

__________________

Date: Thu, 1 Jun 2000 16:59:09 +0900

From: "Michael Engel"

Subject: ORGLIST: cross-posted: preprint servers (2)
Those who receive my email several times, please use the delete key freely.
Coming back to these new preprint servers. There are still so many important

questions open.

Are electronic time-stamps lawyer-attack-proofed ? Or is it necessary for

any preprint server to print out the submitted paper and stamp it manually ?

Will journal publishing companies allow the submission to such servers,

before or after the submission to a journal ?

before submission to a journal: pre-publication ?

after submission to a journal: reduced revenue for the publisher as many

people will not buy the publication but take the preprint ?
Any comments from ChemWeb.com ????
Thank you.

Michael

__________________
Date: Thu, 01 Jun 2000 13:55:39 +0200

From: Shu-Kun Lin

Organization: MDPI (http://www.mdpi.org)

Subject: Re: ORGLIST: Information - Revolution?
Professor Katritzky's (not Dr. Thind's) new journal

and sample collection organization have in every detail

the exactly the same way as our MOLECULES/MDPI (really in every details).

I do not mind because this only shows that the famous professor also

love all of our ideas.
Let us do some good thing together during the internet-information

revolution. My colleagues having worked on MOLECULES/MDPI for 5 years

as the first electron journal of experimental chemistry and the first

journal encouraging sample deposit and exchange are proude of

MOLECULES because we have received support from many chemists including Noble

Prize winners.

Shu-Kun Lin

http://www.mdpi.org

--

Dr. Shu-Kun Lin

Molecular Diversity Preservation International (MDPI)

Saengergasse 25, CH-4054 Basel, Switzerland

Tel. [phone], Fax [phone]

E-mail: [e-mail]

http://www.mdpi.org/lin/

__________________

Date: Thu, 01 Jun 2000 14:37:33 +0200

From: Shu-Kun Lin

Organization: MDPI (http://www.mdpi.org)

Subject: ORGLIST: 2nd International Symposium for Chinese Medicinal Chemists
The 2nd International Symposium for Chinese Medicinal Chemists

(ISCMC 2000) will be held during October 15-19, 2000, in Chengdu, China.

Please visit http://www.mdpi.org/iscmc/ for more details.
The first ISCMC was successfully held in Taipei, July 19-23, 1998.

__________________

Date: Thu, 01 Jun 2000 13:28:29 -0400

From: Jack Sullivan

Subject: ORGLIST: Heck addition of aryl halides to olefins
Pd-catalyzed addition of ArX (X= Br, I) is known to result in mixtures of

regioisomers when olefins are used that contain electrron-donating substituents.

My project involves the reaction of these halides with allyl alcohol to give

3-arylpropanals. Is anyone familiar with any recent references on varying the

reaction conditions (halide, catalyst, etc) to minimize or eliminate this side

product formation? Thank you in advance!

--

Jack Sullivan

__________________
Date: Fri, 2 Jun 2000 12:14:41 +0100

From: "Paul Thind"

Subject: Re: ORGLIST: Information - Revolution?
Dear Friends,
I for one do not wish to conduct this foolish debate in public. Shu-Kun Lin

is having difficulty in understanding basic English. It was his previous

note that stated that it was Paul Thind's new journal which prompted me to

make the position clear.

Now he states that this is Alan Katritzky's journal. This is again wrong.
I have no idea how the journal Molecules is organized. Personally I do not

care. My job is to make clear that Arkivoc belongs only to the ARKAT

Foundation.
Anyone interested in the charter of the ARKAT Foundation or mode of

operation may look on www.arket.org . If anyone is interested in speaking

with myself they may call me on 411 201 9700.
Several months back Dr. Lin in a phone call to me catagorically refused to

help us in developing our web site functionality for online publishing.

I know he sees Arkivoc as competition. This is sad.
We at ARKAT are totally blind to any competition, because we belive in this

project. It will be successful!

I am happy for Shu-Kun Lin to assume that what we are doing is a duplication

of his work. I am not opposed to copying good ideas! I ask Dr. Lin how many

possible ways are there, for publishing online or collecting compound data

online?
Perhaps someone can help us in online submission, viewing, and substructure

searching, ordering, billing etc. of compounds (for free from our web site,

without strings attached!). We have data on about 55,000 compounds. Anyone?

Will the real Dr. Lin, please step forward.
We are happy to recieve any help you can offer. We have a lot to do. It is

my sincere wish that many of you will get involved in this project.

Best wishes,
Paul Thind
P.S. Please note that this is my last message on this subject! You may

e-mail me directly if you have any questions.

__________________
Date: Fri, 2 Jun 2000 16:15:58 +0530

From: "Prof. S. R. Gadre (Faculty@Chemistry)"

Subject: ORGLIST: monograph
Dear Sirs and Madams:

This is to announce an educational monograph entitled "Electrostatics of

Atoms and Molecules" written by S. R. Gadre and R. N. Shirsat which will

be published sometime by July or so by Universities Press (Orient

Longmans). It covers basic introduction starting Coulomb's law,

rigorous and computational results and ends with applications.

Total number of pages is 135 with several color graphics

illustrations.

Proposed price is : US $20 (plus postage and handling).

If interested in details, contact me at [e-mail]

asap. Thanks for your attention.........Shridhar R. Gadre

***********************************************************************

PS. Pl. ignore this mail if you have seen the above message earlier.

We are trying to reach the chemistry community in every possible way.

Any suggestions for this purpose?

June 02,2000.

__________________
Date: Fri, 02 Jun 2000 14:52:39 +0200

From: Shu-Kun Lin

Organization: MDPI (http://www.mdpi.org)

Subject: Re: ORGLIST: Information - Revolution?
We have too many aspects the same (the two guys Lin and Thind are

both from Asia, as Thind is originally from India,

both are in Switzerland; the two organizations are both nonprofit, etc.)

Let us behave differently and have some diversity. Have a nice weekend!

Shu-Kun Lin

E-mail: [e-mail]

http://www.mdpi.org/lin/
__________________
Date: Sat, 03 Jun 2000 13:56:24 IST

From: "Jatin Shah"

Subject: ORGLIST: special filter paper
dear fellow chemists,

does anyone have experience in filtering of sticky organic compounds, which

need to be water washed. the normal filter paper used is not effective and

fibres from the paper come into the product.

also can anyone tell me about an alternate catalyst for iron and acetic

acid, used in the synthesis of paracetamol.

Thanks a lot in advance,

jatin

__________________
Date: Sat, 03 Jun 2000 17:12:13 +0530

From: Faiz Ahmed Khan

Subject: Re: ORGLIST: Heck addition of aryl halides to olefins
Dear Jack,

By varying the 'catalyst cocktail' you can get either 3-arylpropanal or beta-aryl

allyl alcohol (normal Heck product). For example, additives such as silver(I) or

thallium (I) salts give the latter product predominantly. The following review will

be helpful:

A. de Meijere, F.E. Meyer, Angew. Chem. Int. Ed. Engl. 1994, 33, 2379-2411.

(see page: 2382)

good luck,

F.A. Khan

__________________

Date: Sat, 3 Jun 2000 09:03:52 -0500 (EST)

From:

Subject: ORGLIST: Ullmann Biaryl Ether Synthesis
Dear Orglist,
Does anyone know of any good recent reviews on the Ullmann Biaryl

Ether Synthesis?

Thanks,

DMC

__________________
Date: Sat, 03 Jun 2000 16:57:22 GMT

From: "António Dias"

Subject: ORGLIST: DMF
Dear OrgList:

Does anyone know a practical way of getting DMF out of a reaccional

mixture?

Thank you in advance,lab-fellows.

__________________
Date: Sun, 04 Jun 2000 02:31:50 PDT

From: "george zhu"

Subject: ORGLIST: selenium compounds
We are a selenium compounds maker. Pls feel free to contact us for any

technical matter.

Best regards,
George

__________________

Date: Sun, 04 Jun 2000 08:19:25 PDT

From: "Vijay Sane"

Subject: Re: ORGLIST: DMF
Dear Antonio

Could you please tell us what type of your reaction is?

DMF removal will depend on lot of things like, product solubility in water,

as well as in DMF, temperature sensitivity, raw materials and products are

they water sensitive, etc?

Normally one can remove under reduced pressure easily, but agian one needs

to know the boiling points of raw materials as well as products so that they

can be separated.

Regards

vijay sane

>From: "Antsnio Dias"

>To: Multiple recipients of list orglist

>Subject: ORGLIST: DMF

>Date: Sat, 03 Jun 2000 16:57:22 GMT

>

>Dear OrgList:

>Does anyone know a practical way of getting DMF out of a reaccional

>mixture?

>Thank you in advance,lab-fellows.

__________________

Date: Sun, 4 Jun 2000 20:47:03 +0200

From:

Subject: ORGLIST: DMF
Two suggestions:
Saturated aqueous calcium chloride will extract dmf out of organic =

solutions that will otherwise hold dmf strongly.

If your product doesn't tolerate aqueous work up (ypu haven't given many =

details..) then an extraction from heptane into acetonitrile may be an =

option.
Thomas Hoyer

__________________

Date: Mon, 5 Jun 2000 11:54:06 -0500 (GMT)

From: "Dr. D.Basavaiah-(RS)"

Subject: Re: ORGLIST: selenium compounds
Could any of you can enlighten me as to from which sourse I can get the

following compounds in bulk quantity.

1. 4-methyl catechol

2. chloroacetic acid (mono)

3. Salicylic acid (phenol free)

Thank you in advance

krish
**************************************************************************

Research Scholar

School of chemistry Telephone: [phone] extn:4807

University Of Hyderabad

Hyderabad- 500 046

India
e-mail: [e-mail]

**************************************************************************

__________________

Date: Mon, 5 Jun 2000 11:51:23 -0500 (GMT)

From: "Dr. D.Basavaiah-(RS)"

Subject: Re: ORGLIST: Heck addition of aryl halides to olefins
Dear Jack:

You may even try this reference:

Basavaiah et.al Tetrahedron 54(1998) 4943-4948.

krish

**************************************************************************

Research Scholar

School of chemistry Telephone: [phone] extn:4807

University Of Hyderabad

Hyderabad- 500 046

India
e-mail: [e-mail]

**************************************************************************
On Sat, 3 Jun 2000, Faiz Ahmed Khan wrote:
> Dear Jack,

> By varying the 'catalyst cocktail' you can get either 3-arylpropanal or beta-aryl

> allyl alcohol (normal Heck product). For example, additives such as silver(I) or

> thallium (I) salts give the latter product predominantly. The following review will

> be helpful:

> A. de Meijere, F.E. Meyer, Angew. Chem. Int. Ed. Engl. 1994, 33, 2379-2411.

> (see page: 2382)

> good luck,

> F.A. Khan

>

> Jack Sullivan wrote:

>

> > Pd-catalyzed addition of ArX (X= Br, I) is known to result in mixtures of

> > regioisomers when olefins are used that contain electrron-donating substituents.

> > My project involves the reaction of these halides with allyl alcohol to give

> > 3-arylpropanals. Is anyone familiar with any recent references on varying the

> > reaction conditions (halide, catalyst, etc) to minimize or eliminate this side

> > product formation? Thank you in advance!

> > --

> > Jack Sullivan

__________________
Date: Mon, 5 Jun 2000 08:20:15 -0400

From: Kristina Kurz

Subject: ORGLIST: RE: Ullmann Biaryl Ether Synthesis
Hi,
try this:
FREE DATABASE SYNTHESIS REVIEWS
Database of 11,218 English review articles and books of interest to

synthetic organic chemists

Covers literature from 1970 to the end of 1998

Articles and books from over 130 sources which also includes

references not normally cited in Current Contents

Includes original database and three supplements together with

corrections

Updates by annual supplements; release dates of supplements will be

announced in SYNTHESIS

Synthesis Reviews is sponsored by Georg Thieme Verlag and is provided

as a service to the synthetic community. It is not copy-protected and copies can be freely

circulated.

Compiled by:

Professor Philip Kocienski, e-mail: [e-mail]

Dr. Krzysztof Jarowiki, e-mail: [e-mail]

both of Department of Chemistry, University Glasgow, Glasgow G12 8QQ, UK

You find a link at http://www.thieme.de/chemistry/journals.html
Enjoy!
Kristina Kurz, Ph.D.
Managing Editor SYNTHESIS/SYNLETT

Thieme Publisher

333 7th Avenue

New York, NY 10001

phone: [phone]

fax: [phone]

e-mail: [e-mail]

http://www.thieme.de/chemistry/journals.html

> -----Original Message-----

> From: [e-mail] [SMTP:[e-mail]]

> Sent: Saturday, June 03, 2000 9:04 AM

> To: Multiple recipients of list orglist

> Subject: ORGLIST: Ullmann Biaryl Ether Synthesis

>

> Dear Orglist,

>

> Does anyone know of any good recent reviews on the Ullmann Biaryl

> Ether Synthesis?

>

> Thanks,

> DMC

__________________

Date: Mon, 5 Jun 2000 16:32:27 +0200

From: "Yantao Chen"

Subject: ORGLIST: Mitsunobu Inversion
Hi,
Maybe everyone knows the Mitsunobu inversion procedure can make the =

secondary alcohol into the opposite configuration at the alcohol center. =

But sometimes the elimination will occurred when there is also a =

carbonyl group (beta position), in which case the unsaturated carbonyl =

compounds may be obtained instead through the loss of one water =

molecular. How to prevent this? My second question is : Can the aryl =

acid ester (eg. O2N-Ph-COOR) be hydrolyzed using K2CO3/MeOH without no =

water?
Thank you very much.

Yantao Chen

[e-mail]

__________________
Date: Mon, 05 Jun 2000 10:58:51 -0400

From: Jack Sullivan

Subject: Re: ORGLIST: Heck addition of aryl halides to olefins
Thanks to all who responded to my recent inquiry.The answers to my question about

regioisomer control were, of course, in the most recent references and were only

partly available through review articles.

--

Jack Sullivan

__________________
Date: Mon, 05 Jun 2000 17:51:40 GMT

From: "António Dias"

Subject: ORGLIST: DMF tips
Dear lab-fellows:

Thanks to all that contributed to enlighten my DMF-perplexity.

Antonio Dias

__________________

Date: Wed, 7 Jun 2000 14:12:29 -0700

From: "Chapman, Robert D"

Subject: ORGLIST: RE: Y2K
Interestingly, Jacob Zabicky's messages appear to come in 1904 according to

my Macintosh (as quoted immediately following). I know this is the date that

is the beginning of the Universe according to the Motorola CPUs under System

7.x. Is the beginning of the Universe 1970 according to other CPUs, such as

older Intels? Does this mean Jacob's (or his server's) clock is set to a

time before the beginning of the Universe on our individual systems, which

then default to the first known day in the history of time? Also, only those

messages from [e-mail] and not from [e-mail],

which appear OK. I don't really need a reply; these are just observations.

B-)

__________________