From: "Paul Heelis" Subject: New chemistry jobs vacancy site To

Subject: ORGLIST: SPME
I would appreciate it if someone could find

me the following references.

Properties of commercial SPME coatings.

Appl. Solid Phase Microextr. 1999,57-72

Quantitation by SPME before reaching a

partition equilibrium. Appl. Solid Phase Microextr.

1999,22-37

Air sampling with SPME. Appl. Solid Phase

Microextr.1999,159-168

Field analysis by SPME. Appl. Solid Phase

Microextr. 1999,269-283

Metal speciation by SPME-CGC-ICPMS. Appl.

Solid Phase Microextr.1999,296-310

Application of SPME methods for the

determination of volatile wine aroma compounds in view

of the varietal characterization. Appl. Solid Phase

Microextr.

1999,372-392

Quantitative aspects of SPME.Appl.Solid

Phase Microextr. 1999,3-21

SUPELCO.Solid phase microextraction:Theory

and optimization of conditions:SUPELCO. Bulletin

923(R).1998,1-5

Any references about commercial SPME device

made in SUPELCO.

In addition, I want to take this opptunity

to express my discontent.I need the latest references

about SPME. They means a lot to my present work.But I

really don"tknow where I can find them . There are a

lot of jourals in the library.Yes.They are

authoritative journals in their own fields.But it is

impossible that l can find every journal that I need.

For example , Appl. SPME is the kind of journal like

this:it is authoritative in the field of SPME but it

is not so important that it can not be found in every

library. I can't find them in our unversity's library

,not in all the libraries of the city,Chengdu.

So what can I do?

Maybe I can ask my freind to look for these

references for me in the Beijing Library . But I

think that the hope is very slim . Even though there

would be the journals, it is still possible that the

volum of the last year can't be found because they are

being bound.

Maybe I should try to find them on the

internet. There are some on-line databases and they

provide service for searchers.But the service is so

expensive that I don't think that I can afford.And I

think it is not worthwhile.

Searching for references

quickly ,efficiently and precisely is the basical

skill that a reseacher must possess.As a raw reseacher

in the field,I really want to improve my ability.My

complaints above are perhaps a little extreme but I am

longing for find approaches to slove my problems.Did

you encount the same problem as mine ?How did you

overcome the difficulties?Please give me some

suggestion. Thank you very much!

=====

your sincerely Hu Hongkun

_________________
Date: Sat, 27 May 2000 14:44:13 +0800

From: Wei Wang

Organization: SJTU

Subject: ORGLIST: Organic EL
Dear all
Our group's research interests are organic and ploymer EL. Most of our work is to synthesis EL molecules and polymer, such as triphenlyamines derivatives and PPV. Our research interests also include devices fabrication and optimization.
The emerging technology based on organic light emitting materials offers many advantages over existing inorganic electroluminscence and LCD display technology. Organic LED is ideally suitable for portable, battery powered large area flat display device as a result of its high contrast, easily readable images and convenient fabrication.
But the literature of this area is huge and diverse. I have collected a number of useful and interesting archives. To share my own libary with more colleagues, I plan to setup a organic EL website. If anyone is interested, please reply this letter. Suggestions and contributions are welcome. I appreciate your interest and help in any form.

Thanks in advance.

Michael

*********************************************

B98111091 Mail Box

School of Chemistry and Chemical Engineering

Minhang Campus, Shanghai Jiao-Tong Univ.

800 Dong Chuan Road

Minhang, Shanghai CHINA

Zip:200240

Tel:[phone]

Fax:[phone]

Email:[e-mail]

**********************************************

__________________
Date: Sat, 27 May 2000 09:59:49 -0700 (PDT)

From: antonio regla

Subject: ORGLIST: Re: Scientific Information
Dear Members:
I have seen great interest in the subject of scientific information and would like to contribute my opinion on the subject. I agree with most of the opinions that have been given, that the cost of scientific information is very high, and the raw material is provided by the authors for free. True, however authors benefit from publishing their work, they do it to promote their careers, and not only to share information with the scientific community. Many articles will be useful to someone else doing research in related areas, while other articles will not be as useful, I believe a measure of the usefulness so to speak is provided in some kind of citation index where authors can find out how many other scientists have cited their work. One has to consider that journals are a business, because they are not funded by any government agency, they have to hire people to process the submitted articles, to have someone send articles over to referees for review, and finallly print them into a hard copy to be sent out to subscribers. It is very understandable that journal publishers need to make money to stay in business. We are living in capitalistic societies where all human activities are done for profit, and I don't see why we should wonder why publishers do it. Unless they were funded by the government there is no other way for them to stay active other than selling their product. If authors don't want journals to charge so much they should send their publications to free of charge electronic journals, but then, it wouldn't look as good on their resumes to have published in these type of journals. To me, it is easy to understand why things are the way they are. Because we all have contributed one way or the other to make them that way. So why complain now? Let's hope we find new ways of sharing information. Best of luck to everyone.
Sincerely,
Antonio Regla

__________________

Date: Sun, 28 May 2000 04:33:04 -0700 (PDT)

From:

Subject: Melting points
Dear All

I want to help me in finding the melting points of

some organic compounds:

p-bromobenzohydroxamic acid

o-bromobenzohydroxamic acid

m-bromobenzohydroxamic acid

Thank you for help.

A/Hafeez Mohd.

__________________
Date: Sun, 28 May 2000 16:17:29 +0200

From: "Paul Thind"

Subject: Re: ORGLIST: Information - Revolution?
Dear Friends,
I want to make it clear to confused minds that Arkivoc or Arkivod are not my

journals. We have 250 referees from nearly 50 countries and we hope to have

thousands of authors and a lot more readers.
The idea for the Journal was that of Alan Katritzky. The initial donation

has been made by Alan & Linde Katritzky. Alan and Charles Rees have

organized the team (including myself) - to which new people are still being

added. I believe in this project and am simply trying to implementing a

small part of the overall strategy.
The Arkat Foundation is being structured in such a way that no one

individual (not even Alan or I or Charles) will be needed for its survival.

No one person is in charge. We have the Board of Referees, The Scientific

Editors, People in charge of Special Issues and Reviews, and the Technical

Editors and Support Staff. Except for the Support Staff, no one is being

paid!
This is the only way to make it a lasting institution. This may sound corny

... but Arkat is about Chemists helping Chemists. It belongs to you.
I think the arkat web site makes all this very clear.
I do not know enough about MolBank to copy the idea. Donors and customers

will decide who can offer the best product and service.

Yours sincerely,
Paul Thind

__________________

Date: Mon, 29 May 2000 11:07:06 +0200

From: "Dr. F.O. Shode"

Subject: ORGLIST: Typha species
Dear Colleagues,

I need chemical information on Typha species.Can you help? Please.

Regards,

Francis.

__________________
Date: Sun, 10 Jan 1904 16:50:23 +0100

From: Jacob Zabicky

Subject: Re: ORGLIST: Information - Revolution?
Dear friends,
The points of the scientists and educators have amply been made in the

present threadline. At a risk of being a dissonant voice, let me remind you

there are other aspects to consider, some of which were alredy touched,

however scantly.

1. Publishers are there to make a profit, Yes, we say, but profit should be

a "reasonable" one. Let's not forget that's not the way a free market

works. They'll keep on charging whatever they want unless somebody stops

them. The only one to stop them is the buyer by haggling, threatening and

actually cancelling subscriptions. The latter may really be frightening to

publishers, because the costs of production are much higher than those of

reproduction (i.e., printing).
2. Production costs of certain scientific publications are high, however,

today there are many ways of substantially reducing them, without affecting

the quality of the contents or presentation. None of these ways will be

mentioned, but publishers know them well. They are not implemented because

that requires certain changes of editorial policies, and there's no urge

because libraries buy the stuff anyway.

3. Certain publications are oriented towards industry, however, university

libraries can do good use of the information therein. You can subscribe

only at outrageus prices. In fact, industy pays only a fraction of that

price, as the subscription is tax deductable, possibly in more than one

way; no such deduction is applicable to universities as nonprofit

organizations. Unless industry revolts against such overpricing there's

little universities can do about it.
4. The "free" enterprises like the one mentioned by Dr. Shu-Kun Lin (see

below) do not always work so smoothly, possibly due to their limited

capacipty for handling everything on a restricted budget. For example, I

gave it up after addressing several times Dr. Shu-Kun Lin with quetions

relevant to the substances I wanted to send to the MolBank, and getting no

reply. You don't pay and there isn't realy anything to demand from a

good-will organization. On the other hand, if you pay there are potentially

some resources in case your expectations are not satisfied; that's the

stuff other specialists live of.
All he best,
Jacob Zabicky
*******************************************************************

Temporary address:

Prof. Jacob Zabicky Tel.: [phone]

Group de Fisica dels Materials II Fax.: [phone]

Universitat Autonoma de Barcelona Private Tel.: [phone]

08193 Bellaterra (Barcelona)

Spain

*******************************************************************

__________________
Date: Tue, 30 May 2000 23:08:37 +0800

From: "Jeffry Soon"

Subject: ORGLIST: ammonia
Dear all
I was looking the simple process about 1000 L per day of dilution =

ammonia gas into ammonium hydroxide (22-25)%. And the heat produce =

during dilution. please advise
Also, some latest recipe to turn Ammonium nitrate Fertilizer into ANFO =

for blasting rock use. Since, ammonium nitrate explosive grade is =

expensive compare to the fertilizer grade. please advise.
Anybody can show me whether there is some site like this =

question-ask-answer for chemical engineer process. please advise

Jeffery Soon Kong Hieng

South East Asia-MALAYSIA

AJ CHEMICALS SDN BHD.

Quality assurance & Technical Manager.

Bs. Che. Eng.

__________________

Date: Mon, 29 May 2000 09:33:35 -0700 (PDT)

From: antonio regla

Subject: ORGLIST: Re: Thiosemicarbazide Toxicity
Dear List Members,
I would like to ask someone who has prepared thiosemicarbazones in small scale in lab about any possible toxicity. We prepared the thiosemicarbazone of benzaldehyde in a teaching lab, being careful not to spill it on the skin, and noone did. However, we had to warm up the reaction mixture to speed up dissolution of thiosemicarbazide. The solvent was ethanol and the catalyst was a couple of drops of sulfuric acid. There were no noticeable smells in the lab during the experiment. A few students complained of irritation in the face and throat, a minor one, but noticeable nonetheless. I am aware of the reported toxicity of the reagent, but had no idea how the contact with the skin was made. One of my students mentioned to me that she had noticed a bitter taste in her thumb after the experiment, after washing her hands. When I got home that evening I washed my hands well and tasted my thumb out of curiosity, and it was very bitter. I was really puzzled by this, as I didn't touch the reagent myself. I checked Aldrich's Safety book and found information about thiosemicarbazide in a very summarized manner. Apparently it is able to form sulfur and nitrogen oxides by decomposition, I suppose acid catalyzed. What I would like to ask anyone who has handled this reagent is what is the source of the bitter taste in the hands, is it sulfur dioxide? I washed my hands several times and the bitterness still remained. Even the next morning I noticed the bitterness in my thumb. I would appreciate any information anyone could give me regarding this reagent. I have the MSDS for this reagent, I would like to hear about someone who has used it and experienced "bitter thumbs". Next time we use this reagent we will certainly take precautions not to leave hands exposed. Thanks for your attention to this.
Sincerely,
A. Regla
School of Pharmacy
Universidad Autonoma de Morelos

__________________

Date: Mon, 29 May 2000 15:51:34 -0400

From: David Gauthier

Subject: ORGLIST: Fmoc-Asp-OtBu
Dear members,

I'm trying to cristalize Fmoc-Asp-OtBu from a mixture of Fmoc-Asp-OtBu

and Fmoc-Asp(OtBu). I followed Gilles Lajoie's paper in Synthesis

(1990) 571, but still have problems with cristalisation. I would

apreciate if someone could help me.

Regards
David Gauthier

University of Sherbrooke

__________________

Date: Tue, 30 May 2000 09:09:00 +300500

From: "NL Shashidhar"

Subject: Re: ORGLIST: Fmoc-Asp-OtBu
Dear David Gauthier:

I have some experience in preparing both the compounds.

Fmoc-Asp(OtBu)-OH can be separated from Fmoc-Asp-OtBu by repeated

crystallisation using ethylacetate and petroleum ether

Regards

shashidhara.N.L.

associate scientific manager

__________________

Date: Fri, 01 Jan 1904 03:46:14 +0100

From: Jacob Zabicky

Subject: ORGLIST: Re: demand
Hello Nasr,
A recent and extensive review on the Vilsmeier reaction appeared in the

following reference:

G. Jones and S. P. Stanforth, The Vilsmeier reaction of fully conjugated

carbocycles and heterocycles, Organic Reactions, Vol. 49, pp. 1-330 (1997).

Hope you find that useful,
Jacob
*******************************************************************

Temporary address:

Prof. Jacob Zabicky Tel.: [phone]

Group de Fisica dels Materials II Fax.: [phone]

Universitat Autonoma de Barcelona Private Tel.: [phone]

08193 Bellaterra (Barcelona)

Spain

*******************************************************************

__________________
Date: Tue, 30 May 00 16:02:32 +0800

From: zhaojk

Subject: ORGLIST: amine chromatography
Dear all,

Can anybody give me some advice on how to separate the amino alcohol compound

by chromatography method? I use dimethylmethane and CH3OH as the developing

solvent but I find it is difficult to wash them off from the SilGel collum? I

change to Al2O3, but it does not work.
As the polarity of the compound is too large(2 NH2 group and 2 OH group), I

failed several times in the work. I am looking forwad to your reply.

Sincerely yours
Sunshine

__________________

Date: Tue, 30 May 2000 19:46:13 +1000

From: Paul Handley


Subject: ORGLIST: amine chromatography
>Can anybody give me some advice on how to separate the amino alcohol

compound

>by chromatography method? I use dimethylmethane and CH3OH as the developing

>solvent but I find it is difficult to wash them off from the SilGel

collum? I

>change to Al2O3, but it does not work.

>

>As the polarity of the compound is too large(2 NH2 group and 2 OH group), I

>failed several times in the work. I am looking forwad to your reply.
Ive heard a few percent of triethylamine in your column solvent will do

wonders when columning amines

Paul Handley

__________________

Date: Tue, 30 May 2000 15:28:23 +0530 (IST)

From: Dr T Pathak


Subject: Re: ORGLIST:

Use 0.1% Et3N or some other easily removable base throughout if you are

using silica or alumina. Another useful method is to use Dowex/Amberlite

(H+) column if the aminoalcohol is the only amino group containing

material in the mixture. Your compound will stick to the column and all other

components could be washed out. Then use ammonia solution as the eluent

and collect your compound. I have used these techniques several times for

various polar amino compounds and found them very useful.

Good luck!
-----------------------------------------------------------------------------

Dr. Tanmaya Pathak Tel: [phone]

Organic Chemistry Division (Synthesis) 589 33 15/16

National Chemical Laboratory extn.2055/2073

Pune 411 008 (020)-589 31 53

Maharasthra Fax: [phone]

India e.mail: [e-mail]

-----------------------------------------------------------------------------

__________________
Date: Tue, 30 May 2000 12:21:10 +0200

From: Eva Horn Moeller

Subject: Re: ORGLIST: amine chromatography
For the quite difficult polyamines, eluent mixtures such as

dichloromethane - methanol - isopropylamine (e.g. 4:4:1) has been

employed for silica gel chromatography. TEA would probably work fine,

too. These compounds can also be purified using reverse phase-HPLC, with

eluent mixture as e.g. 15% aq. MeCN + 0.1% trifluoroacetic acid. You may

of course try this with a usual column using reverse phase silica gel.

Best regards,

Eva Horn Moeller

(MSc, PhD)

__________________

Date: Tue, 30 May 2000 22:18:18 NZST

From: "kushal Qanungo"

Subject: Re: ORGLIST: amine chromatography
try alumina grade III, elute with neat ether and then approx

20% methanol in ether to be on the safe side, it should elute it off the

column.

Dr. Kushal Qanungo,

SCIB/DRFMC,

CEA-Grenoble,

France

__________________

Date: Tue, 30 May 2000 14:20:09 +0100

From: Jacob Zabicky

Subject: Re: ORGLIST: ammonia
>Date: Fri, 1 Jan 1904 04:24:54 +0100

>To: Jeffry Soon

>From: Jacob Zabicky

>Subject: Re: ORGLIST: ammonia

>Cc:

>Bcc:

>X-Attachments:

>

>Dear Jeffry,

>

>I don't know on which side of the chemical business you are and what are

>the local rules for handling chemicals. My personal view is that you

>should go expensive so you come out cheap: Contract the services of a

>chemical engineer to design a safe contraption. Your problem sounds

>simple, but once you scale up beyond the laboratory scale there are many

>details concerning transfer phenomena, materials, piping, safety and

>regulations that have to be taken into account. One little detail may

>illustrate the thing: You'll probably use as source liquid ammonia in

>cylinders. Letting out ammonia of a cylinder at the rate necessary for

>your desired output may cause fast cooling with considerable slowdown.

>Then you need some heating. How, how much and where to heat are technical

>questions to decide upon.

>

>

>Yours sincerely,

>

>Jacob

*******************************************************************

Temporary address:

Prof. Jacob Zabicky Tel.: [phone]

Group de Fisica dels Materials II Fax.: [phone]

Universitat Autonoma de Barcelona Private Tel.: [phone]

08193 Bellaterra (Barcelona)

Spain

*******************************************************************

__________________
Date: Tue, 30 May 2000 07:02:11 -0700 (PDT)

From:

Subject: ORGLIST: Synthesis of O-ethoxy aniline, O-isoproxy aniline,.....
Dear all,

I want to help me in finding a procedure for synthesis

of five organic compounds from O-aminophenol.

(i) O-hydroxy acetanilide.

(ii) O-ethoxy anilide.

(iii) O-isopropoxy aniline.

(iv) O-cyclohexoxy aniline.

(v) O-sec-butoxy aniline.

thanks,

A/Hafeez Mohamed.

__________________
Date: Tue, 30 May 2000 15:59:17 +0100

From: Jacob Zabicky

Subject: Re: ORGLIST: Synthesis of O-ethoxy aniline, O-isoproxy aniline,.....
Hello Abd-el-Hafeez,
At first sight it seems that besides the first one on your list, you'll

have a hard job starting from o-amino phenol. Unless it is a special

assignment you have, perhaps it will be better for the others to try

1-chloro-2-nitrobenzene or 1-bromo-2-nitrobenzene via nucleophilic

substitution with an alkoxide, followed by reduction of the nitro group.
All the best,
Jacob

>Dear all,

>I want to help me in finding a procedure for synthesis

>of five organic compounds from O-aminophenol.

>(i) O-hydroxy acetanilide.

>(ii) O-ethoxy anilide.

>(iii) O-isopropoxy aniline.

>(iv) O-cyclohexoxy aniline.

>(v) O-sec-butoxy aniline.

> thanks,

>A/Hafeez Mohamed.
*******************************************************************

Temporary address:

Prof. Jacob Zabicky Tel.: [phone]

Group de Fisica dels Materials II Fax.: [phone]

Universitat Autonoma de Barcelona Private Tel.: [phone]

08193 Bellaterra (Barcelona)

Spain

*******************************************************************

__________________