Oligo Name

Solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 (SLC6A3); 5p15.3

AF119117.1 /58554	tgtggtgtagggaacggcctgag aggagcgtgtcctatccccggacgcatgcagggcccccac aggagcgtgtcctatccccggacgcatgcagggcccccac aggagcatgtcctatccctggacgcatgcagggcccccac aggagcgtgtactaccccagaacgcatgcagggcccccac aggagcgtgtactaccccaggacgcatgcagggcccccac tggagcgtgtactaccccaggacgcatgcagggcccccac aggagcgtgtcctatccccggaccggacgcatgcagggcccccac aggagcgtgtactaccccaggacgcatgcagggcccccac aggagcgtgtactaccccaggatgcatgcagggcccccac aggagcgtgtactaccccaggacgcatgcagggcccccat gcaggcagcctgcagaccaacactctgcctggccttgagccgtgacctccaggaag	A10 A9 A11 A7	11 rep: 0.019 As 9 rep: 0.042 As 0.23 Ca 7 rep: 0.009 As	3’UTR		10 repeats =wt Variants: 11, 9, 7	Reduced DAT protein levels
D88556.1 /961	ggccgccgcttgctcccagccatctgcgtccgggaggcgggggcgggggcgcggcccggggaggtgaggaggaggagccaggacgcgagggcgaccccg(T/A)cggcgggagggcggggcggggcggaccctgtctactggataagagcccgaggccgaggctgagaccgcccagcgctgcggagcgggaggggaggcttcgc	-67T>A	0.53 Ca	5’UTR, it creates a SIF binding element			It creates a SIF binding element
AC022130.4 /121577	gccctggagccggataccaaccgccagggctttccaggcccgtcccgggaaatggttttcttaggcgagtgcgaggcgggcccctcggttccgatgcag(G/C)cgcactagatgccggcaaggcggggactaggcctaggggacctcggtcgcctcgaggtcgcggagaccccaaggccacggaaggacccgcgtctccgcag	-660G>C	0.03 Ca	5’UTR			It changes a T-Ag element in a TEF recognition site
AC022130.4 /121756	cgccggggttcgggcgaccctaggggcgacgcacagagctgggcgcggccactcacctcggtgccttctaaggacctggacatcctgggccttggcggcc(C/T)gggggctccattcctccgcgcgctgaatggaagaaatcccgcccgggcatctcggaaggaaagcctcggagtccattcggccctggagccggataccaa	-839C>T	0.45 Ca	5’UTR			It creates a LBP-1 binding site
AC022130.4 /122087	gactccgcagtacccgcccgcagcgcggtgccccacccccctgcgcccgccccgcactccccgcacaccaccactcccctccccgccccccgctcccc(C/G)gctccccggctccggggctggcacccaggcagaaggcactcagggctgtgacttcacgctgagttggaatcaagtgggagcctagtgaccccctggggctg	-1169G>C	0.50 Ca	5’UTR			It replaces a ETF element on EGR-1 regognition site
AC022130.4 /122395	ctgaagtcccctcacctccctggcgatgaagtcccacccctgatgggaggtggtgtcaggaggccttcaggtggtcaggccaggagggctccaccctga(T/G)gaatgggaccagtgccctcataaaacagaccccggagagctctccccagcccctagcgtggggagatacagggagagaactgtctgcaaccccgaagcg	-1476T>G	0.08 Ca	5’UTR			n/a
Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (SULT1A1); 16p12.1
AC020765.6 /140110	tcctgggggacggtggtgtagttggtcatagggttcttcttcatctccttgaacgacgtgtgctgaaccacgaagtccacggtctcctctggcagggag(T/C)gccccacaaactccaggatcttttgaatctcccttttcgggttctgagcagcagagggcccctcagtggaggctcggattactgattcaggaaaagtaaa	R213H HaeII	0.32 Ca	Exon 7		SULT1A1*2	Lower 4-nitrophenol sulphotransferase activity and thermal stability
AC020765.6 /140081	tgaagggggagatgctgtggtccatgaactcctgggggacggtggtgtagttggtcatagggttcttcttcatctccttgaacgacgtgtgctgaacca(C/T)gaagtccacggtctcctctggcagggagCgccccacaaactccaggatcttttgaatctcccttttcgggttctgagcagcagagggcccctcagtggag	M223V	0.010 Ca	Exon 7		SULT1A1*3	Very low Km for 5’-phosphosulfate and 4-nitrophenol
Superoxide dismutase 2, mitochondrial (SOD2); 6q25.3
AL135914.23 /64527	tgccgttcctcggcagcccagcctgcgtagacggtcccgcggcgctgactgaccgggctgtgctttctcgtcttcagcaccagcaggcagctggctccgg(C/T)tttggggtatctgggctccaggcagaagcacagcctccccgacctgccctacgactacggcgccctggaacctcacatcaacgcgcagatcatgcagct	1183C>T V16A -9Ala Bsa WI	0.14 As 0.44 Ca	Exon 1			It falls into the mitochondrial targeting sequence and it may lead to misdirected intracellular trafficking
AL135914.23 /59909	ttacaaagaaaaaaatataatgtatacagtggttgaaaaagtaggagttacaaaaaaatgtgtttgcattttaacttttcaggagatgttacagcccaga(T/C)agctcttcagcctgcactgaagttcaatggtggtggtcatatcaatcatagcattttctggacaaacctcagccctaacggtggtggagaacccaaagg	5777T>C I58T	0 Ca	Exon 3			Affects the stability of the tetrameric interface of MnSOD
Thiopurine S-methyltransferase (TPMT); 6p22.3
AB045146/12225	ctctaaattaaagaaaatatatgcttactctaatataaccctctatttagtcatttgaaaacataatttaagtgtaaatgtatgattttatgcaggttt(G/C)cagaccggggacacagtgtagttggtgtggaaatcagtgaacttgggatacaagaattttttacagagcagaatctttcttactcagaagaaccaatca	238G>C A80P	0-0.005 Ca 0 As	Exon 5		TPMT*2	Low activity
AB045146/16954	accatgggggacgctgctcatcttcttaaagatttgatttttctcccataaaatgttttttctctttctggtaggacaaatattggcaaatttgacatgatttgggatagagga(G/A)cattagttgccattaatccaggtgatcgcaaatggtaagtaatttttctttttttgtttagctgtcttaattttttagtatactata	460G>A A154T	0.039 Ca 0 As	Exon 7		TPMT*3B TPMT*3A	Low activity
AB045146/25270	tcttgtttcaggtaaaatatgcaatatacgttgtcttgagaaggttgatgcttttgaagaacgacataaaagttggggaattgactgtctttttgaaaagttat(A/G)tctacttacagaaaagtaaatgagacatagataaaataaaatcacactgacatgtttttgaggaattgaaaattatgctaaagcctgaaaatgta	719A>G Y240C	0.05 Ca 0.008 As	Exon 10		TPMT*3C TPMT*3A	Low activity
Tumor suppressor protein TP53 (p53); 16p13
NT_010687.2 /207249	gcaatggatgatttgatgctgtccccggacgatattgaacaatggttcactgaagacccaggtccagatgaagctcccagaatgccagaggctgctcccc(G/C)cgtggcccctgcaccagcagctcctacaccggcggcccctgcaccagccccctcctggcccctgtcatcttctgtcccttcccagaaaacctaccagggc	R72P BstUI	0.33 Ca 0.40 As	Exon 4			It may cause a decreased binding to p73
NT_010687.2 /207061	gcagagacctgtgggaagcgaaaattcatgggactgactttctgctcttgtctttcagacttcctgaaaacaacgttctggtaaggacaagggttgggctggggacctggagggctggggggctggggggctgaggacctggtcctctgactgctc	16bp 2X-rep	0.20 Ca	Intron 3		A1 (wt) A2	n/a
UDP glycosiltransferase 1 family, polypeptide A1 (UGT1A1); 2q37
AF297093.1 /174990	gtcacgtgacacagtcaaacattaacttggtgtatcgattggtttttgcca(TA)nagtaggagagggcgaacctctggcaggagcaaa	[TA]6 [TA]5 [TA]7 [TA]8	n=5: 0.05 Ca 0 As 0 H 0 Af n=6: 0.87 As 0.70 Ca 0.38 H 0.75 Af n=7: 0.13 As 0.30 Ca 0.63 H 0 Af n=8: 0.002 Ca 0.25 Af 0 H 0 As	Promoter		UGT1A1*28	Reduced promotor activity and increased serum bilirubin concentration
UDP glycosiltransferase 1 family, polypeptide A7 (UGT1A7);2q37
AF297093/99152	tgccactatcttgaagaaggtgcacagtgccctgctcctctttcctatgtccccagacttctcttagggttctcagacgccatgactttcaaggagagagta(T/C)ggaaccacatcatgcacttggaggaacatttattttgcccctattttttcaaaaatgtcttagaaatagcctctgaa	W208R	0.38 Ca	Exon 1		UGT1A7*4 UGT1A7*3	Low activity
AF297093/98938	ggagttcatggtttttgccgatgctcgctggacggcaccattgcgaagtgcattttctctattaacaagttcatccaatggtatttttgacttatttttttcaaattgcaggagtttgtttaa(T/G)gaccgaaaattagtagaatacttaaaggagagttgttttgatgcagtgtttctcgatccttttgat	N129K	0.62 Ca	Exon 1		UGT1A7*2 UGT1A7*3	Low activity
AF297093/98942-3	ggagttcatggtttttgccgatgctcgctggacggcaccattgcgaagtgcattttctctattaacaagttcatccaatggtatttttgacttatttttttcaaattgcaggagtttgtttaatgac(CG/AA)aaaattagtagaatacttaaaggagagttgttttgatgcagtgtttctcgatccttttgat	R131K	0.62 Ca	Exon 1		UGT1A7*2 UGT1A7*3	Low activity
Xeroderma pigmentosum, complemen-tation group G (ERCC5/XPG); 13q22
AL157769.12 /136886	gaggatgaagagaaaaatcccggagttttttccattaacaattctcccagatattagcatttggttaaaccaagcacttaaaggagtccgggatcgcca(T/C)gggaactcaatagaaaatcctcatcttctcactttgtttcatcggctctgcaaactcttattttttcgaattcgtcctatttttgtgtttgatggggatg	335T>C H46H NcoI	0.46 Am	Exon 2			n/a
AL157769.12 /160371	aaaagaaagaggctttcagattctaaaggaaagaatacatgcggtggatttttgggggagacctgcctctcagaatcatctgatggatcttcaagtgaa(C/G)atgctgaaagttcatctttaatgaatgtacaaaggagaacagctgcgaaagagccaaaaaccagtgcttcagattcgcagaactcagtgaaggaagctcc	3508C>G H1104D	0.22 Am	Exon 15			n/a
X-ray repair cross-complementing DNA repair gene group1 (XRCC1); 19q13.2
L34079.1 /26304	tgcgggaccttagaaggtgacagtgaccaagcttggccagttccgtgtgaaggaggaggatgagagcgccaactctctgaggccgggggctctcttcttcagc(C/T)ggatcaacaagacatccccaggtgagctcggacaacgtgggtcctgagtgagtagggttgagacctagactcgtgggtctgagggtagagggggctggggctcaga	R194W	0.13 Mix	Exon 6			n/a
L34079.1 /27466	tctggggcctggactgctgggtctgagggaggaggggctgggggttgacccccagtggtgctaacctaatctactctttgtcttctccagtgccagctccaactc(G/A)taccccagccacagccccagtccctgcccgagcacagggggcagtgacaggcaaaccccgaggagaaggcaccgagcccagacgaccccgagctggcccagagg	R280H	0.03 Mix	Exon 9			n/a
L34079.1 /28152	caacacccccaagtacagccaggtcctaggcctgggaggccgcatcgtgcgtaaggagtgggtgctggactgtcaccgcatgcgtcggcggctgccctccc(G/A)gaggtaaggcctcacacgccaaccctgctccttatcctgtgctgggcaatgccaggaatctggaggggagtcagactggggcctgccagcggagaacacaggtggtcc	R399Q	0.28 Mix	Exon 10			n/a
X-ray repair cross-complementing DNA repair gene group2 (XRCC2); 7q36.1
AC003109.1 /31479	agctttttactggatagaccgcgtcaatggaggagaaagtgtgaacttacaggagtctactctgaggaaatgttctcagtgcttagagaagcttgtaaatgactatc(G/A)cctggttctttttgcaacgacacaaactataatgcagaaagcctcgagctcatcagaagaaccttctcatgcctctcgacgactgtgtgatgtggacata	R188H	0.05 Mix	Exon 3			n/a
X-ray repair cross-complementing DNA repair gene group3 (XRCC3); 14q32.3
AF037222 /18067	atggctcgcctggtggtcatcgactcggtggcagccccattccgctgtgaatttgacagccaggcctccgcccccagggccaggcatctgcagtccctgggggcca(C/T)gctgcgtgagctgagcagtgccttccagagccctgtgctgtgcatcaaccaggtgagcaccaaggcagggttgcacccctgagctcgtatttttagccaggat	T241M	0.42 Mix	Exon 5			n/a
X-ray repair cross-complementing DNA repair gene group9 (XRCC9); 9p13
AC004472.1 /55417	caccaactcaggtcccaatcagaaaatcatccctccacaccccctctaggaccccgggctcacctgctaaattcactaattgccactttttgggcacccagttgaa(C/A)ccaggcctggccctgaagcaggtgggtggcagagacccagagtgggcagtatggcagttccttggttccttttctggcatcttcccacagccgggacatcttgggtagcagag	V464F	0.01 Mix	Exon 9			n/a
AC004472.1 /56429	tgagcaaggggaacctcacctccccgtctgtaggcacctgcttgctagtatgtgcttggtctggctctgagtgccacaatgaaggggtgaggctaggtcaggtggtg(G/A)cagtagtaattctacctcaatgagaaactgcggggctttggaactgcatgggacattcaaggcctaaaagagaaagaaaaaaattgtatctataatctttg	P330S	0.01 Mix	Exon 7			n/a
AC004472.1 /56667	actagtcaagtcaccccatcacaagcacctcaggaatcctccaccccacatcttcacctggcagttccctacctcaactagcagctccagactctccagctctgct(G/A)ttgtgtcccccagttgctgatagagcctagaggcctccagaagtggaggaccccaggctgatccctctttcagggctgcaaccaagtacaacagtgctctctg	T297I	0.01 Mix	Exon 7			n/a
Xeroderma pigmentosum, complemen-tation groupD (ERCC2/XPD); 19q13.3
L47234.1 /23047	ctgcctgtgcaggcctgtgtgggagtgacgggccagtgtggccaggggtaggggtaggggttggggtggcagggccctggtaaccctgctccccggccccccagat(C/G)ctgcatgccaatgtggtggtttatagctaccactacctcctggaccccaagattgcagacctggtgtccaaggaactggcccgcaaggccgtcgtggtcttcg	I199M	0.01 Mix	Exon 8			n/a
L47234.1 /23051	cctgtgcaggcctgtgtgggagtgacgggccagtgtggccaggggtaggggtaggggttggggtggcagggccctggtaaccctgctccccggccccccagatcctg(C/T)atgccaatgtggtggtttatagctaccactacctcctggaccccaagattgcagacctggtgtccaaggaactggcccgcaaggccgtcgtggtcttcg	H201Y	0.01 Mix	Exon 8			n/a
L47234.1 /23591	gcagcgcctgcgggacgagtaccggcgtctggtggaggggctgcgggaggccagcgccgcccgggagacggacgcccacctggccaaccccgtgctgccc(G/A)acgaagtgctgcagggtgagccccgaccccccgctgccccccagtccctttcccgcctccccgtcgccgctgatagcgtctcctcgcagaggcagtgcct	D312N	0.40 Mix	Exon 10			n/a
L47234.1 /35931	caacagtgcccccctctccctttcctctgttctctgcaggaggatcagctgggcctgtccctgctcagcctggagcagctagaatcagaggagacgctg(A/C)agaggatagagcagattgctcagcagctctgagtggggcgggtggggccataaacggttcctggtgactcctgagtcttgcctggccctggttcccagc	L751Q	0.32 Mix	Exon 23			n/a
Xeroderma pigmentosum, complementation group F (ERCC4/XPF); 16p13.3-p13.11
L76568.1 /16151	aaaagcctttggaagactttatgggtaaatattatcacatagaatgagatatttttatttctctacagaaacaaaaaaggaactggtcctagaaagcaac(C/T)caaagtgggaggcactgactgaagtattaaaagaaattgaggcagaaaataaggagagtgaagctcttggtggtccaggtaggaaaaaaggagatgaaa	P379S	0.03 Mix	n/a			n/a
L76568.1 /17103	gaataagggggcacagggaaactaggaggacaagtgaggtaatagtaacataatgttgttttctattttcaggtcaagtactgatttgtgcaagtgatgacc(G/A)aacatgttcccagctgagagactatatcactcttggagcggaggccttcttattgaggctctacaggaaaacctttgagaaggatagcaaagctgaa	R415Q	0.06 Mix	n/a			n/a

Ca, Caucasians; As, Asians; Af, Africans; AfAm, African Americans; Mex, Mexicans; Mix, frequency evaluated in miscellaneous ethnic groups. N/a = not available.